Evidence map›Paper›PMID 30146584›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Membranous Nephropathy with Crescent after Hematopoietic Cell Transplantation.

Mineaki Kitamura, Satoshi Hisano, Yuka Kurobe, Shinichi Abe, Yuki Ota, Yasushi Sawayama, Tadashi Uramatsu, Yoko Obata, Junya Fukuoka, Yasushi Miyazaki and 2 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Mineaki KitamuraDivision of Blood Purification, Nagasaki University Hospital, Japan.
Satoshi HisanoDepartment of Pathology, Faculty of Medicine, Fukuoka University, Japan.
Yuka KurobeDepartment of Nephrology, Nagasaki University Hospital, Japan.
Shinichi AbeDepartment of Nephrology, Nagasaki University Hospital, Japan.
Yuki OtaDepartment of Nephrology, Nagasaki University Hospital, Japan.
Yasushi SawayamaDepartment of Hematology, Nagasaki University Hospital, Japan.
Tadashi UramatsuDepartment of Nephrology, Nagasaki University Hospital, Japan.
Yoko ObataDepartment of Nephrology, Nagasaki University Hospital, Japan.
Junya FukuokaDepartment of Pathology, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Yasushi MiyazakiDepartment of Hematology, Nagasaki University Hospital, Japan.
Hiroshi MukaeDepartment of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
Tomoya NishinoDepartment of Nephrology, Nagasaki University Hospital, Japan.
Nagasaki University Hospital · JPNagasaki University · JPFukuoka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 44-year-old man who received allogenic hematopoietic stem cell transplantation after being diagnosed with acute myeloid leukemia developed nephrosis when the dose of tacrolimus was tapered. A renal biopsy showed the granular deposition of immunoglobulin G in the glomerular basement membrane and subepithelial electron-dense deposits, crescent formation, C4d-positive staining of the peritubular capillary, and subendothelial swelling, suggesting that the main pathological diagnosis was membranous nephropathy and that chronic graft-versus-host disease played a role in the etiology of nephrosis. We herein report a case of membranous nephropathy with various pathological findings. C4d deposition suggests complement activation and the involvement of humoral factors.

Indexed as

AdultComplement C4bGlomerulonephritis, MembranousGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansLeukemia, Myeloid, AcuteMaleComplement C4bC4d positivity on peritubular capillariescrescentgraft-versus-host diseasemembranous nephropathy

Identifiers

PMID30146584
PMCPMC6367071
OpenAlexW2888024900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.