Evidence map›Paper›PMID 30146562›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Two Cases of Hepatocellular Carcinoma Occurring Immediately after Direct-acting Antiviral Agents against Hepatitis C Virus.

Norihiro Nishijima, Akihiro Nasu, Toru Kimura, Yukio Osaki

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Norihiro NishijimaDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Japan.
Akihiro NasuDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Japan.
Toru KimuraDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Japan.
Yukio OsakiDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Japan.
Osaka Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We experienced two cases of hepatocellular carcinoma (HCC) occurring immediately after treatment with direct-acting antiviral agents (DAAs). Case 1 was a 75-year-old woman in whom HCC was detected immediately after completion of DAA treatment. Case 2 was a 75-year-old woman who had a hypovascular nodule in liver. The hypovascular nodule became hypervascular without enlargement of the nodule size immediately after DAA treatment completion. Although the association between DAA treatment and hepatocarcinogenesis is unknown, sufficient surveillance after achieving a sustained viral response is required, as a large number of patients at a high risk of hepatocarcinogenesis are treated with DAAs.

Indexed as

AgedAntiviral AgentsCarcinoma, HepatocellularCell Transformation, NeoplasticFemaleHepatitis C, ChronicHumansLiver NeoplasmsSustained Virologic ResponseTomography, X-Ray ComputedUltrasonographyAntiviral Agentsdirect-acting antiviral agentshepatitis C virushepatocellular carcinomasustained virological response

Identifiers

PMID30146562
PMCPMC6378164
OpenAlexW2888016046

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.