Evidence map›Paper›PMID 30146558›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Successful Cord Blood Transplantation in a Werner Syndrome Patient with High-risk Myelodysplastic Syndrome.

Kiyohito Hayashi, Taizo Tasaka, Toshinori Kondo, Yuichi Ishikawa, Makoto Goto, Yoshiko Matsuhashi, Yoshito Sadahira, Takashi Sugihara, Hideho Wada

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Case Report: A novelFrontiers in endocrinology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Kiyohito HayashiDepartment of Hematology, Kawasaki Medical School, Japan.
Taizo TasakaDepartment of Hematology, Kawasaki Medical School, Japan.
Toshinori KondoDepartment of Hematology, Kawasaki Medical School, Japan.
Yuichi IshikawaDepartment of Pathology, The Cancer Institute, Japanese Foundation for Cancer Research, Japan.
Makoto GotoDepartment of Rheumatology/Orthopedic Surgery, East Medical Center, Tokyo Women's Medical University, Japan.
Yoshiko MatsuhashiDepartment of Hematology, Kawasaki Medical School, Japan.
Yoshito SadahiraDepartment of Pathology, Kawasaki Medical School, Japan.
Takashi SugiharaDepartment of Hematology, Kawasaki Medical School, Japan.
Hideho WadaDepartment of Hematology, Kawasaki Medical School, Japan.
Kawasaki Medical School · JPJapanese Foundation For Cancer Research · JPSocial Insurance Saitama Chuo Hospital · JPTokyo Women's Medical University Adachi Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Werner syndrome (WS) confers a high risk of the development of neoplasias, including hematological malignancies, and curative treatment for these malignancies is difficult to achieve. A 44-year-old man with myelodysplastic syndrome was admitted to our hospital. He was diagnosed with mutation-proven WS. He underwent cord blood transplantation (CBT) following fludarabine, busulfan, and melphalan administration. A chimerism analysis of his marrow blood on day 62 showed a donor pattern >95%, which confirmed engraftment. The patient lived for 15 months while maintaining remission of MDS without treatment-related toxicity. Our case shows that CBT can be a treatment modality for WS patients with hematological malignancies.

Indexed as

Cord Blood Stem Cell TransplantationAdultAntineoplastic AgentsHumansMaleMyelodysplastic SyndromesTransplantation, HomologousTreatment OutcomeWerner SyndromeAntineoplastic Agentscord blood transplantationmyelodysplastic syndromeWerner syndrome

Identifiers

PMID30146558
PMCPMC6367075
OpenAlexW2888173553

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.