Evidence map›Paper›PMID 30146456›Full record

ReviewTrends in parasitology2018

Plasmodium Parasites Viewed through Proteomics.

Kristian E Swearingen, Scott E Lindner

Abstract readReview
In one paragraph

Review in Trends in parasitology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Microorganisms · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Studies of the Parasite-Midgut Interaction RevealFrontiers in cellular and infection microbiology · 2021
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kristian E SwearingenInstitute for Systems Biology, Seattle, WA 98109, USA; Center for Infectious Disease Research, Seattle, WA 98109, USA.
Scott E LindnerDepartment of Biochemistry and Molecular Biology, Center for Malaria Research, Pennsylvania State University, University Park, PA 16802, USA. Electronic address: Scott.Lindner@psu.edu.

Funding

Mechanisms Governing Translational Regulation During Plasmodium TransmissionR01AI123341 · NIAID · PENNSYLVANIA STATE UNIVERSITY, THE · PI LINDNER, SCOTT E · 2017 to 2021
$1.9M
Elucidating phosphorylation signaling networks in infectious Plasmodium parasitesK25AI119229 · NIAID · INSTITUTE FOR SYSTEMS BIOLOGY · PI SWEARINGEN, KRISTIAN EDWARD · 2015 to 2019
$682k
NIAID NIH HHS K25 AI119229NIAID NIH HHS R01 AI123341
6 · The paper itself

Abstract

Early sequencing efforts that produced the genomes of several species of malaria parasites (Plasmodium genus) propelled transcriptomic and proteomic efforts. In this review, we focus upon some of the exciting proteomic advances from studies of Plasmodium parasites over approximately the past decade. With improvements to both instrumentation and data-processing capabilities, long-standing questions about the forms and functions of these important pathogens are rapidly being answered. In particular, global and subcellular proteomics, quantitative proteomics, and the detection of post-translational modifications have all revealed important features of the parasite's regulatory mechanisms. Finally, we provide our perspectives on future applications of proteomics to Plasmodium research, as well as suggestions for further improvement through standardization of data deposition, analysis, and accessibility.

Indexed as

Protein Processing, Post-TranslationalProteomicsInformation Storage and RetrievalMalariaPlasmodiumProtozoan ProteinsProtozoan Proteinsmalaria parasitesmass spectrometryPlasmodiumpost-translational modificationsproteomicsquantitative proteomics

Identifiers

PMID30146456
PMCPMC6204299

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.