ArticleNeuron2018
Mouse Motor Cortex Coordinates the Behavioral Response to Unpredicted Sensory Feedback.
Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 61 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
61 citing papers in PubMed, 134 citations in OpenAlex.
- Abstract Representation of Movement Parameters in Basal Ganglia Output.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
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- Distinct sensorimotor encoding in tuft dendrites and somata associated with action, correction, and learning.bioRxiv : the preprint server for biology · 2026Article
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- Motor cortex directly excites the substantia nigra pars reticulata, the basal ganglia output nucleus.Nature communications · 2026Article
- A transparent wheel-based platform for locomotion-on-demand and multi-view body and facial kinematics in head-fixed mice.Scientific reports · 2026Article
- 'Backpropagation and the brain' realized in cortical error neuron microcircuits.PLoS computational biology · 2026Article
- Autogenic spinal excitatory circuit ensures skilled hand movements in primates.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Distinct roles of cortical layer 5 subtypes in associative learning.Nature communications · 2026Article
- Mouse sensorimotor cortex reflects complex kinematic details during reaching and grasping.eLife · 2026Article
- Sleep and infant development in the first year.Pediatric research · 2026Article
- Widefield cortical activity and functional connectivity during motorized locomotion.Communications biology · 2026Article
- Interactions between motor cortical forelimb regions and their influence on muscles reorganize across behaviors.Nature communications · 2025Article
- Three systems of circuit formation: assembly, updating and tuning.Nature reviews. Neuroscience · 2025Review
- Two-photon fiberscope with a proactive optoelectrical commutator for rotational resistance-free imaging in freely behaving rodents.Neurophotonics · 2025Article
- Article
- VTA projections to M1 are essential for reorganization of layer 2-3 network dynamics underlying motor learning.Nature communications · 2025Article
- Site-specific seeding of Lewy pathology induces distinct pre-motor cellular and dendritic vulnerabilities in the cortex.Nature communications · 2024Article
- The role of motor cortex in motor sequence execution depends on demands for flexibility.Nature neuroscience · 2024Article
- Learning and Control in Motor Cortex across Cell Types and Scales.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
1 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motor cortex (M1) lesions result in motor impairments, yet how M1 contributes to the control of movement remains controversial. To investigate the role of M1 in sensory guided motor coordination, we trained mice to navigate a virtual corridor using a spherical treadmill. This task required directional adjustments through spontaneous turning, while unexpected visual offset perturbations prompted induced turning. We found that M1 is essential for execution and learning of this visually guided task. Turn-selective layer 2/3 and layer 5 pyramidal tract (PT) neuron activation was shaped differentially with learning but scaled linearly with turn acceleration during spontaneous turns. During induced turns, however, layer 2/3 neurons were activated independent of behavioral response, while PT neurons still encoded behavioral response magnitude. Our results are consistent with a role of M1 in the detection of sensory perturbations that result in deviations from intended motor state and the initiation of an appropriate corrective response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.