ArticleHand (New York, N.Y.)2019
Morbid Obesity Increases the Risk of Postoperative Wound Complications, Infection, and Repeat Surgical Procedures Following Upper Extremity Limb Salvage Surgery for Soft Tissue Sarcoma.
Article in Hand (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Association of Obesity With Survival Outcomes in Patients With Cancer: A Systematic Review and Meta-analysis.JAMA network open · 2021Pooled it
- Practical dose ranges supporting target vancomycin exposure with AUC-guided dosing in overweight and obese patients: A multicentre retrospective study.British journal of clinical pharmacology · 2026Article
- Regenerative potential of PRP-based scaffolds in chronic wound healing: Mechanisms, advances, and therapeutic insights.Regenerative therapy · 2025Review
- Impact of Postoperative Infection on Lower Limb Function After Surgery for Malignant Bone and Soft Tissue Tumors: Data from a Nationwide Registry in Japan.Current oncology (Toronto, Ont.) · 2025Article
- Effects of postoperative hand therapy in patients with Dupuytren's disease : A prospective hyperspectral imaging study.Orthopadie (Heidelberg, Germany) · 2025Article
- Morbid Obesity and Diabetes Increase the Risk of Reoperation following Microvascular Decompression: A National Surgical Quality Improvement Program Analysis of 1,303 Patients.Journal of neurological surgery. Part B, Skull base · 2025Article
- Visceral fat area and subcutaneous fat area as measures of body composition in soft tissue sarcoma.Journal of surgical oncology · 2024Article
- Effects of Postoperative Splinting on Outcomes following Digital Mucous Cyst Excision: A Retrospective Review.Journal of hand and microsurgery · 2024Article
- Prevalence of and risk factors for surgical site infections after pancreaticoduodenectomy: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2024Review
- Immediate Plastic Surgery Intervention after Soft Tissue Sarcoma Resection: Examining Wound Healing, Readmission, and Reoperation.Plastic and reconstructive surgery. Global open · 2023Article
- Survival analysis based on body mass index in patients with Covid-19 admitted to the intensive care unit of Amir Al-Momenin Hospital in Arak - 2021.Obesity medicine · 2022Article
- Review
- Surgical management of sarcoma in adolescent and young adult patients.BMC research notes · 2020Article
- Extremity Soft Tissue Sarcoma: Role of Local Control.Current treatment options in oncology · 2020Review
- High Glucose Variability Increases 30-Day Readmission Rates in Patients with Type 2 Diabetes Hospitalized in Department of Surgery.Scientific reports · 2019Article
- Human Wounds and Its Burden: An Updated Compendium of Estimates.Advances in wound care · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundObesity is a known risk factor for wound complications; however, unlike elective upper extremity procedures, where obesity can be modified preoperatively, excision of soft tissue sarcomas (STSs) is not elective, and as such, obesity cannot be modified. There is a paucity of data concerning the impact of obesity on wound healing in upper extremity sarcoma surgery.
methodsA total of 261 (159 males and 102 females) patients with a STS of the upper extremity from 2006-2014 were reviewed. The mean age and body mass index (BMI) were 56 (18-97) years and 26.6 (15.4-40.8) kg/m
resultsForty-nine patients (19%) sustained a wound dehiscence, delayed healing, or infection. Class III obesity increased the risk of wound complications (hazard ratio [HR] = 8.19, 95% confidence interval [CI] = 1.96-22.96, P < .001) and infection (HR = 10.09, 95% CI = 1.60-34.83, P = .01). There was no difference in the mean TESS (93 vs 90, P = .13) or MSTS93 (95 vs 93, P = .39) between obese and nonobese patients.
conclusionsThe results of this study indicate morbid obesity significantly increased the risk of a postoperative wound complication and infection. However, following upper extremity limb salvage surgery, obese patients should expect to have excellent functional outcome.
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Registered trials
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