Evidence map›Paper›PMID 30145850›Full record

ArticleHuman brain mapping2019

Abnormal neural response to phonological working memory demands in persistent developmental stuttering.

Yang Yang, Fanlu Jia, Peter T Fox, Wai Ting Siok, Li Hai Tan

Open access · bronzeAbstract read
In one paragraph

Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. A Meta-Analytical Review of Executive Function Skills in Adults Who Stutter.Journal of speech, language, and hearing research : JSLHR · 2026
    Pooled it
  2. Trial
  3. Review
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  7. Review
  8. Article
  9. Network Models for Assessing the Co-occurrence Between Stuttering and ADHD.International journal of language & communication disorders
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Yang YangCenter for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen, China.ORCID 0000-0001-5306-7274
Fanlu JiaCenter for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen, China.
Peter T FoxCenter for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen, China.
Wai Ting SiokDepartment of Linguistics, University of Hong Kong, Pokfulam Road, Hong Kong.
Li Hai TanCenter for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen, China.
Shenzhen University · CNThe University of Texas Health Science Center at San Antonio · USUniversity of Hong Kong · HK

Funding

the Guangdong Pearl River Talents Plan Innovative and Entrepreneurial Team grant 2016ZT06S220the Shenzhen Fundamental Research Project JCYJ20160608173106220the Shenzhen Fundamental Research Project JCYJ20170307155304424the Shenzhen Fundamental Research Project JCYJ20170412164413575the Shenzhen Fundamental Research Project JCYJ20170818110022721the Shenzhen Fundamental Research Project JCYJ20170818110103216the Shenzhen Fundamental Research Project JCYJ20170818110126127the Shenzhen Peacock Plan KQTD2015033016104926
6 · The paper itself

Abstract

Persistent developmental stuttering is a neurological disorder that commonly manifests as a motor problem. Cognitive theories, however, hold that poorly developed cognitive skills are the origins of stuttering. Working memory (WM), a multicomponent cognitive system that mediates information maintenance and manipulation, is known to play an important role in speech production, leading us to postulate that the neurophysiological mechanisms underlying stuttering may be associated with a WM deficit. Using functional magnetic resonance imaging, we aimed to elucidate brain mechanisms in a phonological WM task in adults who stutter and controls. A right-lateralized compensatory mechanism for a deficit in the rehearsal process and neural disconnections associated with the central executive dysfunction were found. Furthermore, the neural abnormalities underlying the phonological WM were independent of memory load. This study demonstrates for the first time the atypical neural responses to phonological WM in PWS, shedding new light on the underlying cause of stuttering.

Indexed as

ConnectomeAdultBrainFemaleHumansMagnetic Resonance ImagingMaleMemory, Short-TermNerve NetStutteringYoung Adultbrain activationdevelopmental stutteringfunctional connectivityphonological working memory

Identifiers

PMID30145850
PMCPMC6865627
OpenAlexW2888353858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.