ArticleLasers in medical science2019
Effects of Nd:YAG laser irradiation on the growth of Candida albicans and Streptococcus mutans: in vitro study.
Article in Lasers in medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Effectiveness of lasers and aPDT in elimination of intraoral halitosis: a systematic review based on clinical trials.Lasers in medical science · 2022Pooled it
- Short-term results of the combined application of neodymium-doped yttrium aluminum garnet (Nd:YAG) laser and erbium-doped yttrium aluminum garnet (Er:YAG) laser in the treatment of periodontal disease: a randomized controlled trial.Clinical oral investigations · 2021Trial
- Effect of ozone and diode laser (635 nm) in reducing orthodontic pain in the maxillary arch-a randomized clinical controlled trial.Lasers in medical science · 2020Trial
- Comparative evaluation of the effects of laser and chemical denture disinfectants on the surface characteristics of CAD-CAM and conventional denture resins: An in vitro experimental study.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2026Article
- Antimicrobial effect of 1064 nm Nd:YAG laser with flat-top homogeneous beam profile on oral fungal and bacterial biofilms: an in vitro study.Lasers in medical science · 2026Article
- Antibiofilm efficacy of 1,064-nm neodymium-doped yttrium aluminum garnet laser onMicrobiology spectrum · 2026Article
- The Effect of the ErMaterials (Basel, Switzerland) · 2026Article
- Evaluation of the Influence of Er:YAG Laser Parameters on the Effectiveness of Growth Inhibition ofJournal of clinical medicine · 2025Article
- The Effect of Laser Surface Treatment on the Bond Strength of Adhesive Materials to Primary Teeth: A Systematic Review.Materials (Basel, Switzerland) · 2025Review
- Antibacterial Effects of Er:YAG Laser Irradiation onLife (Basel, Switzerland) · 2025Article
- Comparing the Effect of Photodynamic Therapy With 660 and 450 nm Lasers and Cold Atmospheric Plasma onJournal of lasers in medical sciences · 2025Article
- Effect of Nd:YAG Laser Irradiation on the Growth of Oral Biofilm.Microorganisms · 2024Article
- Multiphotonic Ablation and Electro-Capacitive Effects Exhibited byBioengineering (Basel, Switzerland) · 2024Article
- Different wavelengths of laser: are they significant for treatment of denture stomatitis?: an in-vitro study.BMC oral health · 2024Article
- What can we learn from treatments of oral lichen planus?Frontiers in cellular and infection microbiology · 2024Review
- Efficacy of Various Laser Wavelengths in the Surgical Treatment of Ankyloglossia: A Systematic Review.Life (Basel, Switzerland) · 2022Review
- The effect of photodynamic therapy by gold nanoparticles on Streptococcus mutans and biofilm formation: an in vitro study.Lasers in medical science · 2022Article
- Influence of Incubation Time on Ortho-Toluidine Blue Mediated Antimicrobial Photodynamic Therapy Directed against SelectedInternational journal of molecular sciences · 2021Article
- Photobiomodulation with Red and Near-Infrared Light Improves Viability and Modulates Expression of Mesenchymal and Apoptotic-Related Markers in Human Gingival Fibroblasts.Materials (Basel, Switzerland) · 2021Article
- The Effect of Er:YAG Lasers on the Reduction of Aerosol Formation for Dental Workers.Materials (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to evaluate the effects of Nd:YAG laser with flat-top handpiece on the in vitro growth of Candida albicans and Streptococcus mutans. The incidence of C. albicans (opportunistic commensal) and S. mutans (facultatively anaerobic) infections is increasing, despite available treatments. Cultures of Streptococcus mutans and Candida albicans were irradiated using Nd:YAG laser (LightWalker, Fotona) with flat-top handpiece (Genova, LightWalker, Fotona) at the following parameters: group G1: 0.25 W, 10 Hz, 15 s, 3 J and group G2: 1 W, 10 Hz, 60s, 59 J. The results were evaluated directly and 24 h after irradiation using a quantitative culture method (estimation of colony-forming units in 1 ml of suspension, cfu/ml), and microscopic analysis with Janus green stain and compared with control group in which laser was not applied. C. albicans was reduced by 20 up to 54% for G1, and for G2 by 10 up to 60% directly after the application. The cfu/ml values for S. mutans decreased by 13% (p = 0.1771) for G1 and 89% (p < 0.0001) for G2. In both test groups 24 h after the application, the number of colony-forming units decreased by 15-46% for G1 and by 15-64% for G2. The arrested cell division, increasing the surface area and increasing the number of metabolically inactive cells, were observed in morphometric analysis. Macroscopic and microscopic analyses revealed a reduction in cell number and a significant decrease of cell metabolism after laser application for both C. albicans and S. mutans.
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Registered trials
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