Evidence map›Paper›PMID 30145361›Full record

ArticleAcademic pediatrics

INSIGHT Study Maternal Return to Work and Infant Weight Outcomes.

Sally G Eagleton, Emily E Hohman, Nicole Verdiglione, Leann L Birch, Ian M Paul, Jennifer S Savage

Registry-linked trialAbstract read
In one paragraph

Article in Academic pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01167270 (The Intervention Nurses Start Infants Growing on Healthy Trajectories), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01167270 nacompletednot on this map

The Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) Study

TypeinterventionalSponsorIan M. Paul, MDRan2012 to 2023Enrolled316ConditionsInfant, ObesityArmsChild Safety Insights, Parenting Insights
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sally G EagletonCenter for Childhood Obesity Research (SG Eagleton, EE Hohman, and JS Savage) and Department of Nutritional Sciences (SG Eagleton and JS Savage), Penn State College of Health and Human Development, University Park, Pa; Department of Foods and Nutrition, University of Georgia (LL Birch), Athens, Ga. Electronic address: jfs195@psu.edu.
Emily E HohmanCenter for Childhood Obesity Research (SG Eagleton, EE Hohman, and JS Savage) and Department of Nutritional Sciences (SG Eagleton and JS Savage), Penn State College of Health and Human Development, University Park, Pa.
Nicole VerdiglionePediatrics and Public Health Sciences, Penn State College of Medicine (N Verdiglione and IM Paul), Hershey, Pa.
Leann L BirchDepartment of Foods and Nutrition, University of Georgia (LL Birch), Athens, Ga.
Ian M PaulPediatrics and Public Health Sciences, Penn State College of Medicine (N Verdiglione and IM Paul), Hershey, Pa.
Jennifer S SavageCenter for Childhood Obesity Research (SG Eagleton, EE Hohman, and JS Savage) and Department of Nutritional Sciences (SG Eagleton and JS Savage), Penn State College of Health and Human Development, University Park, Pa; Department of Foods and Nutrition, University of Georgia (LL Birch), Athens, Ga.

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
Preventing Obesity through Intervention during InfancyR01DK088244 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI PAUL, IAN M, WILLIAMS, JENNIFER SAVAGE · 2011 to 2022
$7.0M
NRSA Training CoreTL1TR002016 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI THOMAS, GAIL D. · 2016 to 2025
$3.4M
NCATS NIH HHS TL1 TR002016NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR002014NIDDK NIH HHS R01 DK088244
6 · The paper itself

Abstract

objectiveMaternal return to work within 12 weeks of delivery is associated with poor child health and development. However, little is known about the impact of return to work on the risk of child obesity. We examined whether timing of maternal return to work is associated with rapid infant weight gain from 0 to 6 months and weight-for-length at 1 year.

methodsSecondary data analysis of 279 mother-newborn dyads from the Intervention Nurses Start Infants Growing on Healthy Trajectories Study, a randomized controlled trial evaluating a responsive parenting (RP) intervention. Rapid infant weight gain from 0 to 6 months was assessed using conditional weight gain (CWG) scores. Infant weight-for-length was calculated using World Health Organization reference values. Analysis of variance (ANOVA) examined whether infant weight outcomes differed by timing of maternal return to work (≤12 weeks vs >12 weeks after delivery). Moderation by study group (RP intervention vs safety control) and mediation by breastmilk feeding were examined in ANOVA models.

resultsAmong 261 mothers, approximately one half (n = 130) returned to work within 12 weeks. Compared with infants of mothers who returned to work after 12 weeks, infants of mothers who returned to work within 12 weeks had greater CWG scores from 0 to 6 months (P = .006) and were heavier at 1 year (P = .05). These associations were not moderated by study group or mediated by breastmilk feeding.

conclusionsMaternal return to work within 12 weeks was associated with rapid infant weight gain in the first 6 months and greater weight-for-length at 1 year, although the mechanisms to explain our findings are unclear.

Indexed as

MothersReturn to WorkWeight GainAdultBreast FeedingFemaleHumansInfantMaleParental LeavePediatric ObesityTime FactorsYoung Adultchildhood obesityFamily and Medical Leave Actinfant growthmaternal employmentrapid weight gain

Identifiers

PMID30145361
PMCPMC6321792

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.