ArticleNeuroImage2018
Altered functional network connectivity relates to motor development in children born very preterm.
Article in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed.
- Altered connectivity and network efficiency in preterm infants.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Environmental roots of neonatal health: how social and structural exposures shape early-life outcomes.Pediatric research · 2026Review
- Functional connectivity patterns as an early indicator of later very early preterm outcomes.Developmental cognitive neuroscience · 2026Article
- Early Life Resting-State Network Functional Connectivity and Long-Term Neurodevelopmental Outcomes after Neonatal Encephalopathy.AJNR. American journal of neuroradiology · 2026Article
- Motor performance and higher associative cortical networks in adolescents with neonatal hypoxic-ischaemic encephalopathy treated with therapeutic hypothermia.Developmental medicine and child neurology · 2026Article
- Article
- Does the Maternal Gut Microbiome Influence the Outcome of Perinatal Asphyxia?Antioxidants (Basel, Switzerland) · 2025Review
- Functional development of the human cerebellum from birth to age five.Nature communications · 2025Article
- Statistical properties of functional connectivity MRI enrichment analysis in school-age autism research.Developmental cognitive neuroscience · 2025Article
- Functional Connectivity Relationships to Longitudinal Motor Outcomes Differ in Very Preterm Children With and Without Brain Injury.Neurology. Clinical practice · 2025Article
- Inhibition abilities and functional brain connectivity in school-aged term-born and preterm-born children.Pediatric research · 2025Article
- Brain volumes are related with motor skills at late childhood in children born extremely preterm.PloS one · 2025Article
- Functional connectivity as a prognostic biomarker for neurodevelopmental outcomes in preterm infants without severe brain injury.Brain communications · 2025Article
- DFC-Igloo: A dynamic functional connectome learning framework for identifying neurodevelopmental biomarkers in very preterm infants.Computer methods and programs in biomedicine · 2024Article
- Functional connectivity of the pediatric brain.Neuroradiology · 2024Review
- Advances in Fetal Brain Imaging.Magnetic resonance imaging clinics of North America · 2024Review
- The developmental phenotype of motor delay in extremely preterm infants following early-life respiratory adversity is influenced by brain dysmaturation in the parietal lobe.Journal of neurodevelopmental disorders · 2024Article
- Network-level enrichment provides a framework for biological interpretation of machine learning results.Network neuroscience (Cambridge, Mass.) · 2024Article
- Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer's disease.Brain : a journal of neurology · 2023Article
- Development of neonatal brain functional centrality and alterations associated with preterm birth.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Individuals born very preterm (<32 weeks gestation) are at increased risk for neuromotor impairments. The ability to characterize the structural and functional mechanisms underlying these impairments remains limited using existing neuroimaging techniques. Resting state-functional magnetic resonance imaging (rs-fMRI) holds promise for defining the functional network architecture of the developing brain in relation to typical and aberrant neurodevelopment. In 58 very preterm and 65 term-born children studied from birth to age 12 years, we examined relations between functional connectivity measures from low-motion rs-fMRI data and motor skills assessed using the Movement Assessment Battery for Children, 2nd edition. Across all subscales, motor performance was better in term than very preterm children. Examination of relations between functional connectivity and motor measures using enrichment analysis revealed between-group differences within cerebellar, frontoparietal, and default mode networks, and between basal ganglia-motor, thalamus-motor, basal ganglia-auditory, and dorsal attention-default mode networks. Specifically, very preterm children exhibited weaker associations between motor scores and thalamus-motor and basal ganglia-motor network connectivity. These findings highlight key functional brain systems underlying motor development. They also demonstrate persisting developmental effects of preterm birth on functional connectivity and motor performance in childhood, providing evidence for an alternative network architecture supporting motor function in preterm children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.