Evidence map›Paper›PMID 30144347›Full record

ArticleThe European journal of neuroscience2020

The molecular genetics of human sleep.

Luoying Zhang, Ying-Hui Fu

Open access · bronzeAbstract read
In one paragraph

Article in The European journal of neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Sleep physiology and critical illness: A narrative review.Journal of the Intensive Care Society · 2026
    Review
  2. Article
  3. Review
  4. Brain Clocks, Sleep, and Mood.Advances in experimental medicine and biology · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Luoying ZhangKey Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology and Institute of Brain Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Ying-Hui FuDepartment of Neurology, University of California, San Francisco, California.ORCID 0000-0002-6628-0266
Huazhong University of Science and Technology · CNUniversity of California, San Francisco · US

Funding

Investigating the neurocircuitry of sleep duration regulationR01NS104782 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FU, YING-HUI · 2018 to 2022
$3.0M
Investigating Genetics of Human Natural Short SleepersR01NS072360 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FU, YING-HUI · 2011 to 2015
$2.2M
Natural Science Foundation of China 31471125Natural Science Foundation of China 31671360NIH HHS NS072360NIH HHS NS104782NINDS NIH HHS R01 NS072360NINDS NIH HHS R01 NS104782One Thousand Talents Program of ChinaWilliam Bowes Neurogenetics Fund
6 · The paper itself

Abstract

It has been known for many years that genetic influences account for some of the individual differences in human sleep parameters, but the underlying molecular mechanisms remain unclear. With major advances of molecular biology and the recognition of heritable sleep behaviors in humans over the past 30 years, a number of genetic variants have been identified to be associated with human sleep timing, duration and quality, both in healthy individuals and under pathological conditions. Some of these variants were further validated and characterized in animal models, shedding light on the mechanism of how these variants likely alter sleep in humans, which may provide new insights into developing more effective treatments to improve human sleep.

Indexed as

SleepSleep Wake DisordersAnimalsCircadian RhythmHumansIndividualityModels, AnimalMolecular Biologyanimal modelgenetic variantsleep disorderssleep homeostasissleep phase

Identifiers

PMID30144347
PMCPMC6389443
OpenAlexW2888685664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.