ArticleHuman brain mapping2018
Genetic influences on neonatal cortical thickness and surface area.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01409746 (Early Brain Development in Twins), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Early Brain Development in Twins
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Genetic Influences on the Developing Young Brain and Risk for Neuropsychiatric Disorders.Biological psychiatry · 2023Pooled it
- Heritability of Psychological Traits and Developmental Milestones in Infancy: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Fractal analysis of brain shape formation predicts age and genetic similarity in human newborns.Nature neuroscience · 2026Article
- Cortical Structure Abnormalities in Patients With Noise-Induced Hearing Loss: A Surface-Based Morphometry Study.Brain and behavior · 2025Article
- White matter microstructure and functional connectivity in the brains of infants with Turner syndrome.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Revealing Fine-grained Genetically Informed Cortical Parcellation Maps of Neonates Based on Multi-view Spectral Clustering.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024Article
- Family socioeconomic status and adolescent substance use: The role of parent-adolescent brain similarity and parental monitoring.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2024Article
- CBLL1 is hypomethylated and correlates with cortical thickness in transgender men before gender affirming hormone treatment.Scientific reports · 2023Article
- Structural brain correlates of non-verbal cognitive ability in 5-year-old children: Findings from the FinnBrain birth cohort study.Human brain mapping · 2023Article
- Human-specific evolutionary markers linked to foetal neurodevelopment modulate brain surface area in schizophrenia.Communications biology · 2023Article
- The effects of cytomegalovirus on brain structure following sport-related concussion.Brain : a journal of neurology · 2023Article
- Mapping Genetic Topography of Cortical Thickness and Surface Area in Neonatal Brains.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Genetic and Environmental Variation in Continuous Phenotypes in the ABCD Study®.Behavior genetics · 2023Article
- Structural neuroimaging phenotypes and associated molecular and genomic underpinnings in autism: a review.Frontiers in neuroscience · 2023Review
- Mapping developmental regionalization and patterns of cortical surface area from 29 post-menstrual weeks to 2 years of age.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Influence of gonadal steroids on cortical surface area in infancy.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Genetic Influences on Longitudinal Trajectories of Cortical Thickness and Surface Area during the First 2 Years of Life.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Altered gray matter structural covariance networks in drug-naïve and treated early HIV-infected individuals.Frontiers in neurology · 2022Article
- Neural and behavioral signatures of social evaluation and adaptation in childhood and adolescence: The Leiden consortium on individual development (L-CID).Developmental cognitive neuroscience · 2020Review
- Extra-axial Cerebrospinal Fluid Relationships to Infant Brain Structure, Cognitive Development, and Risk for Schizophrenia.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
Genetic and environmental influences on cortical thickness (CT) and surface area (SA) are thought to vary in a complex and dynamic way across the lifespan. It has been established that CT and SA are genetically distinct in older children, adolescents, and adults, and that heritability varies across cortical regions. Very little, however, is known about how genetic and environmental factors influence infant CT and SA. Using structural MRI, we performed the first assessment of genetic and environmental influences on normal variation of SA and CT in 360 twin neonates. We observed strong and significant additive genetic influences on total SA (a
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.