Evidence map›Paper›PMID 30144098›Full record

ArticleMedical physics2018

Machine learning and modeling: Data, validation, communication challenges.

Issam El Naqa, Dan Ruan, Gilmer Valdes, Andre Dekker, Todd McNutt, Yaorong Ge, Q Jackie Wu, Jung Hun Oh, Maria Thor, Wade Smith and 8 more

Abstract read
In one paragraph

Article in Medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. A convolutional neural network model for EPID-based non-transit dosimetry.Journal of applied clinical medical physics · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. The role of machine learning in HIV risk prediction.Frontiers in reproductive health · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Issam El NaqaDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Dan RuanDepartment of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA.
Gilmer ValdesDepartment of Radiation Oncology, University of California Los San Francisco, San Francisco, CA, USA.
Andre DekkerGROW-School for Oncology and Developmental Biology, Department of Radiation Oncology (MAASTRO), Maastricht University Medical Center, Maastricht, The Netherlands.
Todd McNuttDepartment of Radiation Oncology, John Hopkins University, Baltimore, MD, USA.
Yaorong GeDepartment of Software and Information Systems, University of North Carolina, Charlotte, NC, USA.
Q Jackie WuDepartment of Radiation Oncology, Duke University Medical Center, Durham, NC, USA.
Jung Hun OhDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Maria ThorDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Wade SmithDepartment of Radiation Oncology, University of Washington, Seattle, WA, USA.
Arvind RaoDepartment of Radiation Oncology, MD Anderson, Houston, TX, USA.
Clifton FullerDepartment of Radiation Oncology, MD Anderson, Houston, TX, USA.
Ying XiaoDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA.
Frank ManionDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Matthew SchipperDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Charles MayoDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Jean M MoranDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.
Randall Ten HakenDepartment of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
TREATMENT VERIFICATION AND TREATMENT PLAN REFINEMENTP01CA059827 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KESSLER, MARC LEWIS, LAWRENCE, THEODORE S · 1993 to 2018
$37.9M
NCI NIH HHS P01 CA059827NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

With the era of big data, the utilization of machine learning algorithms in radiation oncology is rapidly growing with applications including: treatment response modeling, treatment planning, contouring, organ segmentation, image-guidance, motion tracking, quality assurance, and more. Despite this interest, practical clinical implementation of machine learning as part of the day-to-day clinical operations is still lagging. The aim of this white paper is to further promote progress in this new field of machine learning in radiation oncology by highlighting its untapped advantages and potentials for clinical advancement, while also presenting current challenges and open questions for future research. The targeted audience of this paper includes newcomers as well as practitioners in the field of medical physics/radiation oncology. The paper also provides general recommendations to avoid common pitfalls when applying these powerful data analytic tools to medical physics and radiation oncology problems and suggests some guidelines for transparent and informative reporting of machine learning results.

Indexed as

CommunicationDatabases, FactualMachine LearningMedical InformaticsRadiation OncologyReproducibility of Resultsbig datamachine learningradiation oncology

Identifiers

PMID30144098
PMCPMC6181755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.