ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2019
Dose variability in different lymph node levels during locoregional breast cancer irradiation: the impact of deep-inspiration breath hold.
Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Reproducibility of repeated breathhold and impact of breathhold failure in whole breast and regional nodal irradiation in prone crawl position.Scientific reports · 2022Trial
- Impact of guideline changes on adoption of hypofractionation and breast cancer patient characteristics in the randomized controlled HYPOSIB trial.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2021Trial
- Deep-inspirational breath-hold (DIBH) technique in left-sided breast cancer: various aspects of clinical utility.Radiation oncology (London, England) · 2021Trial
- Improving Quality Assurance in a Radiation Oncology Using ARIA Visual Care Path.Journal of personalized medicine · 2024Article
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- Advances and potential of optical surface imaging in radiotherapy.Physics in medicine and biology · 2022Review
- Intrafraction motion during radiotherapy of breast tumor, breast tumor bed, and individual axillary lymph nodes on cine magnetic resonance imaging.Physics and imaging in radiation oncology · 2022Article
- Article
- AlignRTReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2022Article
- Immobilization-assisted abdominal deep inspiration breath-hold in post-mastectomy radiotherapy of left-sided breast cancer with internal mammary chain coverage.Quantitative imaging in medicine and surgery · 2021Article
- Recent advanced in Surface Guided Radiation Therapy.Radiation oncology (London, England) · 2020Review
- Stability and reproducibility of 6013 deep inspiration breath-holds in left-sided breast cancer.Radiation oncology (London, England) · 2020Article
- An Update on Regional Nodal Irradiation: Indication, Target Volume Delineation, and Radiotherapy Techniques.Breast care (Basel, Switzerland) · 2020Review
- Recent advances in radiotherapy of breast cancer.Radiation oncology (London, England) · 2020Review
- Impact of surface-guided positioning on the use of portal imaging and initial set-up duration in breast cancer patients.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2019Article
- Left breast irradiation with tangential intensity modulated radiotherapy (t-IMRT) versus tangential volumetric modulated arc therapy (t-VMAT): trade-offs between secondary cancer induction risk and optimal target coverage.Radiation oncology (London, England) · 2019Article
- Which target volume should be considered when irradiating the regional nodes in breast cancer? Results of a network-meta-analysis.Radiation oncology (London, England) · 2019Article
- Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAim of the present analysis was to evaluate the movement and dose variability of the different lymph node levels of node-positive breast cancer patients during adjuvant radiotherapy (RT) with regional nodal irradiation (RNI) in deep-inspiration breath hold (DIBH).
methodsThirty-five consecutive node-positive breast cancer patients treated from October 2016 to February 2018 receiving postoperative RT of the breast or chest wall including RNI of the supra-/infraclavicular lymph node levels (corresponding to levels IV, III, Rotter LN (interpectoral), and some parts of level II) were analyzed. To evaluate the lymph node level movement, a center of volume (COV) was obtained for each lymph node level for free-breathing (FB) and DIBH plans. Geometric shifts and dose differences between FB and DIBH were analyzed.
resultsA significant movement of the COV in anterior (y) and cranial (z) dimensions was observed for lymph node levels I-II and Rotter lymph nodes (p < 0.001) due to DIBH. Only minor changes in the lateral dimension (x axis) were observed, without reaching significance for levels III, IV, and internal mammary. There was a significant difference in the mean dose of level I (DIBH vs. FB: 38.2 Gy/41.3 Gy, p < 0.001) and level II (DIBH vs. FB: 45.9 Gy/47.2 Gy, p < 0.001), while there was no significant difference in level III (p = 0.298), level IV (p = 0.476), or internal mammary nodes (p = 0.471).
conclusionA significant movement of the axillary lymph node levels was observed during DIBH in anterior and cranial directions for node-positive breast cancer patients in comparison to FB. The movement leads to a significant dose reduction in level I and level II.
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