Evidence map›Paper›PMID 30143690›Full record

ArticleScientific reports2018

Comprehensive in vitro and in vivo studies of novel melt-derived Nb-substituted 45S5 bioglass reveal its enhanced bioactive properties for bone healing.

Lucas Souza, João Henrique Lopes, Davi Encarnação, Italo Odone Mazali, Richard Alan Martin, José Angelo Camilli, Celso Aparecido Bertran

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lucas SouzaDepartment of Structural and Functional Biology, Institute of Biology, University of Campinas - UNICAMP, 13083-862, Campinas, SP, Brazil.ORCID 0000-0002-0188-5168
João Henrique LopesDepartment of Physical Chemistry, Institute of Chemistry, University of Campinas - UNICAMP, P.O. Box 6154, 13083-970, Campinas, SP, Brazil. henriquelopez@gmail.com.ORCID 0000-0001-6872-0299
Davi EncarnaçãoDepartment of Physical Chemistry, Institute of Chemistry, University of Campinas - UNICAMP, P.O. Box 6154, 13083-970, Campinas, SP, Brazil.
Italo Odone MazaliLaboratory of Functional Materials, Department of Inorganic Chemistry, Institute of Chemistry, University of Campinas - UNICAMP, P.O. Box 6154, 13083-970, Campinas, SP, Brazil.ORCID 0000-0001-5698-5273
Richard Alan MartinSchool of Engineering & Aston Research Centre for Healthy Ageing, Aston University, B47ET, Birmingham, United Kingdom.
José Angelo CamilliDepartment of Structural and Functional Biology, Institute of Biology, University of Campinas - UNICAMP, 13083-862, Campinas, SP, Brazil.
Celso Aparecido BertranDepartment of Physical Chemistry, Institute of Chemistry, University of Campinas - UNICAMP, P.O. Box 6154, 13083-970, Campinas, SP, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRAston University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present work presents and discusses the results of a comprehensive study on the bioactive properties of Nb-substituted silicate glass derived from 45S5 bioglass. In vitro and in vivo experiments were performed. We undertook three different types of in vitro analyses: (i) investigation of the kinetics of chemical reactivity and the bioactivity of Nb-substituted glass in simulated body fluid (SBF) by

Indexed as

AnimalsApatitesBiocompatible MaterialsCeramicsEmbryonic Stem CellsFluorescenceGlassHumansKidneyLiverMagnetic Resonance SpectroscopyNiobiumOrgan SizeOsteogenesisRatsTibiaApatitesbioactive glass 45S5Biocompatible MaterialsNiobium

Identifiers

PMID30143690
PMCPMC6109119
OpenAlexW2888191465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.