Evidence map›Paper›PMID 30143078›Full record

ArticleThe Journal of investigative dermatology2018

Are MicroRNAs Key to Developing Biomarkers for Cutaneous T-Cell Lymphoma?

Maria Estela Martinez-Escala, Jaehyuk Choi

Abstract readComment
In one paragraph

Article in The Journal of investigative dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maria Estela Martinez-EscalaDepartment of Dermatology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
Jaehyuk ChoiDepartment of Dermatology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA; Department of Biochemistry and Molecular Genetics, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA. Electronic address: jaehyuk.choi@northwestern.edu.
Northwestern University · US

Funding

The Role of ZEB1 Mutations in Cutaneous T Cell LymphomaK08CA191019 · NCI · YALE UNIVERSITY · PI CHOI, JAEHYUK · 2015 to 2019
$760k
NCI NIH HHS K08 CA191019
6 · The paper itself

Abstract

MicroRNAs are noncoding molecules that induce epigenetic modulation, and they have been involved in tumorigenesis of solid and hematologic malignancies, including cutaneous T-cell lymphoma. MicroRNAs appear to play a role in cutaneous T-cell lymphoma pathogenesis and in disease progression. We comment on recent efforts to develop microRNA classifiers that improve cutaneous T-cell lymphoma diagnosis and predict disease course.

Indexed as

Lymphoma, T-Cell, CutaneousMicroRNAsBiomarkersCell Transformation, NeoplasticHumansPrognosisBiomarkersMicroRNAs

Identifiers

PMID30143078
PMCPMC6561652
OpenAlexW2888505365

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.