Evidence map›Paper›PMID 30142972›Full record

ArticleMolecules (Basel, Switzerland)2018

In Vitro Ecological Response of the Human Gut Microbiome to Bioactive Extracts from Edible Wild Mushrooms.

Emanuel Vamanu, Florentina Gatea, Ionela Sârbu

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Article
  3. Life (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Overall Dietary Quality Relates to Gut Microbiota Diversity and Abundance.International journal of molecular sciences · 2019
    Article
  15. Pharmaceutics · 2019
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Emanuel VamanuUniversity of Agronomic Science and Veterinary Medicine, Faculty of Biotechnology, 59 Marasti Blvd, 1 District, 011464 Bucharest, Romania. email@emanuelvamanu.ro.ORCID 0000-0002-3376-2058
Florentina GateaCentre of Bioanalysis, National Institute for Biological Sciences, 296 Spl. Independentei, 060031 Bucharest, Romania. flori_g_alexia@yahoo.com.
Ionela SârbuICUB-Research Institute of the University of Bucharest, 36⁻46 Bd. M. Kogalniceanu, 5th District, 050107 Bucharest, Romania. ionela24avram@yahoo.com.
National Institute of Research and Development for Biological Sciences · ROUniversity of Agronomic Sciences and Veterinary Medicine of Bucharest · ROUniversity of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents the effect of two new products based on atomized extracts from edible wild mushrooms (RoBioMush1, RoBioMush2) on the microbiota of three target groups: clinically healthy (NG) individuals, individuals with nutritional disorders (ND), and individuals with cardiovascular diseases (CVD). The microbiota fingerprints were determined by quantitative polymerase chain reaction (qPCR). Modulations in the simulated microbiome were established and correlated with the presence of phenolic compounds released in the in vitro environment (a three-stage culture system GIS2 simulator, www.gissystems.ro). The high metabolizing capacity of NG and CVD correlated positively with the rest of the biological activities expressed in vitro. ND microbiota consumed a wide spectrum of monosaccharides from the products. Xylose was present in large quantities in the descending segment (minimum: 175 μg/mL for ND). The primary conclusion was that the microbiological ecosystem was modulated, as proven by the presence of specific biomarkers (e.g., ammonium levels and fingerprints of short-chain fatty acids⁻SCFAs), which stimulate the organism's health status and were correlated with the restoration of a normal microbiota fingerprint.

Indexed as

AgaricalesGallic AcidGastrointestinal MicrobiomeHumansMicrobiotaPolymerase Chain ReactionXyloseGallic AcidXyloseBoletusgallic acidin vitromicrobiotamushroomthree stage culture system

Identifiers

PMID30142972
PMCPMC6225291
OpenAlexW2888625591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.