Evidence map›Paper›PMID 30142971›Full record

ArticleInternational journal of molecular sciences2018

In-Gyeong Yun, Sun-Hee Ahn, Weon-Jong Yoon, Chang Sook Kim, Yun Kyong Lim, Joong-Ki Kook, Seunggon Jung, Choong-Ho Choi, Tae-Hoon Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Journal of dental sciences · 2025
    Article
  4. Host mRNA Analysis of Periodontal Disease Patients Positive forInternational journal of molecular sciences · 2022
    Review
  5. Vanillin Derivatives ReverseFrontiers in pharmacology · 2022
    Article
  6. Comparing the nasal bacterial microbiome diversity of allergic rhinitis, chronic rhinosinusitis and control subjects.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  7. Molecules (Basel, Switzerland) · 2020
    Article
  8. International journal of molecular sciences · 2020
    Article
  9. Article
  10. Inhibitory Effects ofInternational journal of molecular sciences · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

In-Gyeong YunDepartment of Preventive and Public Health Dentistry, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju 61186, Korea. heavenstairs@naver.com.ORCID 0000-0003-1170-7135
Sun-Hee AhnDepartment of Oral Biochemistry, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju 61186, Korea. sun3193@jnu.ac.kr.ORCID 0000-0002-0772-9588
Weon-Jong YoonJeju Biodiversity Research Institute (JBRI), Jeju Technopark (JTP), Jeju 63608, Korea. yyjkl@jejutp.or.kr.
Chang Sook KimJeju Biodiversity Research Institute (JBRI), Jeju Technopark (JTP), Jeju 63608, Korea. cskim@jejutp.or.kr.
Yun Kyong LimDepartment of Oral Biochemistry, School of Dentistry, Chosun University, Gwangju 61452, Korea. dbsruddl77@hanmail.net.
Joong-Ki KookDepartment of Oral Biochemistry, School of Dentistry, Chosun University, Gwangju 61452, Korea. jkkook@chosun.ac.kr.
Seunggon JungDepartment of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University, Gwangju 61186, Korea. ashgray79@gmail.com.
Choong-Ho ChoiDepartment of Preventive and Public Health Dentistry, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju 61186, Korea. hochoi@chonnam.ac.kr.ORCID 0000-0002-6803-3218
Tae-Hoon LeeDepartment of Oral Biochemistry, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju 61186, Korea. thlee83@jnu.ac.kr.ORCID 0000-0003-0105-1750
Chonnam National University · KRChosun University · KRJeju TechnoPark · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal disease, a chronic disease caused by bacterial infection, eventually progresses to severe inflammation and bone loss. Regulating excessive inflammation of inflamed periodontal tissues is critical in treating periodontal diseases. The periodontal ligament (PDL) is primarily a connective tissue attachment between the root and alveolar bone. PDL fibroblasts (PDLFs) produce pro-inflammatory cytokines in response to bacterial infection, which could further adversely affect the tissue and cause bone loss. In this study, we determined the ability of

Indexed as

AdultAnti-Inflammatory AgentsBicuspidCell SurvivalCoculture TechniquesFibroblastsFusobacterium nucleatumHealthy VolunteersHumansInterleukin-1betaInterleukin-6Interleukin-6 InhibitorsInterleukin-8LipopolysaccharidesLitseaMolarAnti-Inflammatory AgentsIL1B protein, humanIL6 protein, humanInterleukin-1betaInterleukin-6Interleukin-6 InhibitorsInterleukin-8LipopolysaccharidesPlant ExtractsIL-6IL-8inflammationLitsea japonica leaf extractperiodontal diseaseperiodontal ligament

Identifiers

PMID30142971
PMCPMC6163774
OpenAlexW2888527856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.