SynthesisMedicine2018
Anterior cervical discectomy and fusion versus hybrid surgery in multilevel cervical spondylotic myelopathy: A meta-analysis.
Synthesis in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 34 citations in OpenAlex.
- Ultrasound Images under an Optimized Image Processing Algorithm in Guiding the Neurological Safety of Resection of Lumbar Disc Nucleus Pulposus in Spinal Surgery.Computational and mathematical methods in medicine · 2022Trial
- Efficacy and safety of epidural steroid injection following discectomy for patients with lumbar disc herniation: A protocol.Medicine · 2020Trial
- Comparative Outcomes of Anterior Cervical Discectomy and Fusion Vs Hybrid Surgery in Multilevel Cervical Degenerative Disc Disease: A Systematic Review and Meta-analysis.International journal of spine surgery · 2026Article
- Expandable corpectomy cage with articulating endcap for correction of severe cervical kyphotic deformity: a case report.Journal of spine surgery (Hong Kong) · 2026Article
- Biomechanical effects of a novel anatomic fusion cage for anterior cervical corpectomy: a finite element study.BMC musculoskeletal disorders · 2026Article
- Outcomes of microscopy‑assisted anterior cervical discectomy and fusion in a selected cohort with soft giant cervical disc herniation‑induced cervical spondylotic myelopathy.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Article
- Kinematic status of Bryan and Mobi-C artificial cervical discs post cervical hybrid surgery: a retrospective study.Journal of orthopaedic surgery and research · 2024Article
- Anterior cervical hybrid constructs reduce superior adjacent segment burden compared to multilevel anterior cervical discectomy and fusion.Journal of spine surgery (Hong Kong) · 2024Article
- Application and Advantages of the Trans-Unco-Discal (TUD) Approach for Cervical Spondylotic Myelopathy and Radiculopathy: Classification and Modification of Surgical Technique Based on the Location of Spinal Cord and/or Nerve Root Compression.Journal of clinical medicine · 2024Article
- No Difference in Two-Year Revisions Between Hybrid Fusion and Two-Level Anterior Discectomy and Fusion: A National Database Study.Global spine journal · 2024Article
- Using Piezosurgery in Anterior Cervical Discectomy and Fusion to Treat Complex Cervical Spondylotic Myelopathy Is Safe and Effective.Advances in orthopedics · 2023Article
- Sagittal sequence and clinical efficacy of cervical disc replacement and hybrid surgery in the treatment of cervical spondylotic myelopathy: a retrospective study.Frontiers in surgery · 2023Article
- Outcomes of cervical degenerative disc disease treated by anterior cervical discectomy and fusion with self-locking fusion cage.World journal of clinical cases · 2022Article
- Hybrid Anterior Cervical Discectomy and Fusion and Cervical Disc Arthroplasty: An Analysis of Short-Term Complications, Reoperations, and Readmissions.Global spine journal · 2021Article
- Anterior hybrid construction of multilevel cervical disc disease and spondylotic spinal stenosis: surgical results and factors affecting adjacent segment problems.Journal of orthopaedic surgery and research · 2021Article
- Anterior Cervical Corpectomy and Fusion for Degenerative and Traumatic Spine Disorders, Single-Center Experience of a Case Series of 119 Patients.Operative neurosurgery (Hagerstown, Md.) · 2020Article
- Hybrid decompression and reconstruction technique for cervical spondylotic myelopathy: case series and review of the literature.Journal of spine surgery (Hong Kong) · 2020Review
- Article
- Multivariate analysis of poor outcome after anterior surgery in multilevel cervical spondylotic myelopathy patients with heterotopic ossification and preoperative kyphotic alignment.Therapeutics and clinical risk management · 2019Article
- Anterior cervical discectomy and fusion versus hybrid surgery in multilevel cervical spondylotic myelopathy: A meta-analysis: Erratum.Medicine · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveA meta-analysis was performed to compare the radiographic and surgical outcomes between anterior cervical discectomy and fusion (ACDF) and hybrid surgery (HS, corpectomy combined with discectomy) in the treatment for multilevel cervical spondylotic myelopathy (mCSM). SUMMARY OF BACKGROUND DATA: Both ACDF and HS are used to treat mCSM, however, which one is better treatment for mCSM remains considerable controversy.
methodsAn extensive search of literature was searched in PubMed/Medline, Embase, the Cochrane library, CNKI, and WANFANG databases on ACDF versus HS treating mCSM from January 2011 to December 2017. The following variables were extracted: blood loss, operation time, fusion rate, Cobb angles of C2-C7, total complications, dysphagia, hoarseness, C5 palsy, infection, cerebral fluid leakage, epidural hematoma, and graft subsidence. Data analysis was conducted with RevMan 5.3 and STATA 12.0.
resultsA total of 4 studies including 669 patients were included in our study. The pooled analysis showed that there were no significant difference in the operation time, fusion rate, Cobb angles of C2-C7, dysphagia, hoarseness, C5 palsy, infection, cerebral fluid leakage, epidural hematoma, and graft subsidence. However, there were significant difference between 2 groups in blood loss [P < .00001, SMD = -30.29 (-45.06, -15.52); heterogeneity: P = .38, I = 0%= and total complications [P = .04, OR = 0.66 95%CI (0.44, 0.98); heterogeneity: P = .37, I = 4%].
conclusionsBased on our meta-analysis, except for blood loss and total complications, both ACDF and hybrid surgery are effective options for the treatment of multilevel cervical spondylotic myelopathy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.