Evidence map›Paper›PMID 30142768›Full record

Trial reportMedicine2018

A randomized, open phase IV exploratory clinical trial to evaluate the efficacy and safety of acupuncture on the outcome of induction of ovulation in women with poor ovarian response: A study protocol for a randomized controlled trial.

Hoyoung Lee, Tae-Young Choi, Eun Hyoung Shim, Jiae Choi, Jong Kil Joo, Bo Sun Joo, Myeong Soo Lee, Jun-Yong Choi, Ki-Tae Ha, Sooseong You and 1 more

Open access · goldAbstract readClinical Trial, Phase IVComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Hoyoung LeeClinical Medicine Division, Korea Institute of Oriental Medicine, Yuseong-gu, Daejeon Integrative Health Promotion Team, Korea Health Promotion Institute, Jung-gu, Seoul Department of Obstetrics and Gynecology, Pusan National University, Seo-gu, Busan Infertility Institute, Pohang Women's Hospital, Pohang-si, Gyenonsangbuk-do Department of Internal Medicine, Korean Medicine Hospital of Pusan National University, Yangsan, Gyeongsangnam Department of Korean Medical Science, School of Korean Medicine and Korean Medical Research Center for Healthy Aging, Pusan National University, Yangsan, Gyeongsangnam, Republic of Korea.
Tae-Young Choi
Eun Hyoung Shim
Jiae Choi
Jong Kil Joo
Bo Sun Joo
Myeong Soo Lee
Jun-Yong Choi
Ki-Tae Ha
Sooseong You
Kyu Sup Lee
Korea Institute of Oriental Medicine · KRKorea Health Promotion Institute · KRPusan National University · KRSunlin University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWomen with infertility who have a poor ovarian responder (POR), characterized by a low number of retrieved oocytes after ovulation induction, often have a significantly reduced pregnancy rate after in vitro fertilization-embryo transfer (IVF-ET), due to the few transferred embryos. Acupuncture is a form of Korean Traditional Medicine. It involves the insertion of a microscopic needle at a specific point in the body, known as an acupuncture point or an acupoint. In this study, our purpose is to investigate how acupuncture affects the retrieval of mature oocytes after ovulation induction in patients with POR. METHODS AND ANALYSIS: This study will be a randomized clinical trial comprising an IVF-ET trial and an IVF-ET trial after acupuncture. Seventy patients will by enrolled and randomly assigned to either of the 2 groups. The study subjects will be required to be diagnosed as having POR. Participants will be divided into 2 groups: IVF-ET single treatment group, and acupuncture and IVF-ET combined treatment group. The study subjects will be required to participate in a 15-week trial involving 16 acupuncture treatments over a period of approximately 2 months before ovulation induction for oocyte retrieval. The primary assessment of all participants will be comparing the number of oocytes.

resultThis treatment will be a therapeutic model for POR. DISCUSSION: Our results will provide patients with POR as well as complementary and alternative medicine professionals, such as Korean medicine doctors, about the potential role of acupuncture in the treatment of POR. This will improve the quality of life in women with infertility and provide an important treatment option for patients with POR. Further studies can be performed to determine the optimal treatment for POR.

Indexed as

Pregnancy RateAcupuncture PointsAcupuncture TherapyAdultFemaleFertilization in VitroHumansInfertility, FemaleOocyte RetrievalOvulation InductionPregnancyTreatment OutcomeYoung Adult

Identifiers

PMID30142768
PMCPMC6113045
OpenAlexW2888191182

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.