SynthesisMedicine2018
Arterial lactate in predicting mortality after paraquat poisoning: A meta-analysis.
Synthesis in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Serum creatinine in predicting mortality after paraquat poisoning: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Squalene epoxidase promotes paraquat-induced pulmonary toxicity through endoplasmic reticulum-mediated ferroptosis.Journal of advanced research · 2026Article
- Clinical characteristics and early admission predictors of in-hospital death in acute paraquat poisoning: a retrospective cohort study of 128 patients.Frontiers in medicine · 2026Article
- Sociodemographic and clinical characteristics related to the final condition of patients intoxicated by paraquat in a hospital in southwestern ColombiaBiomedica : revista del Instituto Nacional de Salud · 2022Observational
- Effects of sequential blood purification on the organ function and lethality in patients with paraquat-induced multiple organ dysfunction syndrome.American journal of translational research · 2022Article
- An analysis of 1344 consecutive acute intoxication cases admitted to an academic emergency medicine department in Turkey.Northern clinics of Istanbul · 2021Article
- Small molecule proteomics quantifies differences between normal and fibrotic pulmonary extracellular matrices.Chinese medical journal · 2020Article
- Hyperamylasemia as an early predictor of mortality in patients with acute paraquat poisoning.The Journal of international medical research · 2020Article
- The significance of serum HMGB1 level in humans with acute paraquat poisoning.Scientific reports · 2019Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to explore the effects of arterial lactate as a predictor of mortality in patients with paraquat (PQ) poisoning.
methodsThe databases PubMed, EMBase, Web of Science, ScienceDirect, Cochrane library, and studies published until 31 February 2018 were searched. The data were extracted to perform pooled analysis, heterogeneity testing, sensitivity analysis, publication bias analysis, and Fagan plot analysis.
resultsPooled analysis showed that a high arterial lactate was significantly correlated with poor mortality (pooled odds ratio = 16.94, 95% confidence interval [CI]: 7.96-36.08, P < .001). The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio were 77% (95% CI: 0.69-0.84), 84% (95% CI: 0.74-0.90), 4.7 (95% CI: 2.9-7.8), 0.28 (95% CI: 0.20-0.39), and 17 (8-36), respectively. An area under the curve of 0.87 (95% CI: 0.83-0.89) means a high ability for prognostic detection.
conclusionOur findings show that arterial lactate is an effective predictor of mortality in patients with PQ poisoning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.