Evidence map›Paper›PMID 30142757›Full record

ArticleMedicine2018

Effectiveness and safety of Chinese herbal medicine formula Gualou Xiebai Banxia (GLXBBX) decoction for the treatment of stable angina pectoris: Protocol for a systematic review.

Mingtai Chen, Meihuan Li, Lijun Ou, Rongren Kuang, Yingnan Chen, Tao Li, Ling Men, Jian Zhang, Zhong Zhang

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. 1-Deoxynojirimycin in Mulberry (Frontiers in pharmacology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mingtai ChenCardiovascular Department, Shenzhen Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine Shenzhen Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, Shenzhen, Guangdong Fuwai Hospital Chinese Academy of Medical Sciences, Beijing, China.
Meihuan Li
Lijun Ou
Rongren Kuang
Yingnan Chen
Tao Li
Ling Men
Jian Zhang
Zhong Zhang
Guangzhou University of Chinese Medicine · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStable angina pectoris (SAP) is one of the most common symptoms of coronary heart disease. Chinese herbal medicine (CHM) has been used to treat SAP increasingly due to its less side effects. The subject of this study is to explore the effectiveness and safety of Gualou Xiebai Banxia (GLXBBX) decoction as a kind of CHM for SAP.

methodsA systematic literature search for articles up to June 2018 will be performed in following electronic databases: PubMed, Embase, the Cochrane Library, China National Knowledge Infrastructure, Chinese Scientific Journals Database, Chinese Biomedical Database, Chinese Biomedical Literature Service System (SinoMed), and Wanfang Database. Inclusion criteria are randomized controlled trials of modified GLXBBX decoction applied on patients with SAP. The primary outcome measures will be coronary heart disease-related clinical evaluation (frequency of acute attack angina, severity of angina pectoris, electrocardiographic changes, and amount of nitroglycerin) and adverse events. RevMan 5.3 software will be used for data synthesis, sensitivity analysis, metaregression, subgroup analysis, and risk of bias assessment. A funnel plot will be developed to evaluate reporting bias and Egger tests will be used to assess funnel plot symmetries. We will use the Grading of Recommendations Assessment, Development and Evaluation system to assess the quality of evidence.

resultsThis systematic review study will provide an evidence of GLXBBX decoction for SAP.

conclusionThe study will give an explicit evidence to evaluate the effectiveness and safety of GLXBBX decoction for SAP. ETHICS AND DISSEMINATION: This systematic review does not require ethics approval and will be submitted to a peer-reviewed journal. PROSPERO REGISTRATION NUMBER: CRD 42018094538.

Indexed as

Angina, StableDrugs, Chinese HerbalFemaleHumansMalePhytotherapyRandomized Controlled Trials as TopicSystematic Reviews as TopicTreatment OutcomeDrugs, Chinese Herbalgualou xiebai baijiutang

Identifiers

PMID30142757
PMCPMC6113022
OpenAlexW2888389974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.