Evidence map›Paper›PMID 30142749›Full record

ArticleMedicine2018

Clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (BoNT).

Lili Bai, Xiaobo Peng, Yanqing Liu, Yawei Sun, Xin Wang, Xingwang Wang, Guodong Lin, Peng Zhang, Kun Wan, Zewu Qiu

Abstract read
In one paragraph

Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Iatrogenic botulism: a risk for botulinum toxin's medical use?Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  4. Article
  5. Article
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  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. The whole truth about botulinum toxin - a review.Postepy dermatologii i alergologii · 2020
    Review
  18. Article
  19. Review
  20. Interpol review of toxicology 2016-2019.Forensic science international. Synergy · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lili BaiDepartment of Poisoning Treatment, Affiliated Hospital, Academy of Military Medical Science, Poisoning Treatment Center of the Army, Beijing, China.
Xiaobo Peng
Yanqing Liu
Yawei Sun
Xin Wang
Xingwang Wang
Guodong Lin
Peng Zhang
Kun Wan
Zewu Qiu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to analyze the clinical characteristics of and treatment strategies for botulism among patients receiving cosmetic injection of botulinum toxin (BoNT).A total of 86 botulism patients caused by cosmetic injection of BoNT were enrolled in our study. All of the patients were diagnosed according to their history of cosmetic BoNT injection, clinical symptoms and signs, and other auxiliary examinations (including those on renal and liver functions, blood index detection, and chest X-ray). All of the patients received comprehensive treatments and botulinum antitoxin serum injection.The main symptoms of botulism patients included headache, dizziness, insomnia, fatigue, blurred vision, eye opening difficulty, slurred speech, dysphagia, bucking, constipation, and anxiety. These clinical symptoms occurred 0∼36 days after BoNT injection, especially from 2nd to 6th day after the operation. Furthermore, the usage dose of BoNT was negatively related to latent period. Finally, patients all discharged from our hospital 1∼20 days after treatments, and their symptoms relieved or disappeared.Botulism is a severe side effect for BoNT injection. Injecting botulinum antitoxin serum may be an effective approach to improve clinical outcomes of botulism cases.

Indexed as

AdolescentAdultBotulinum AntitoxinBotulinum ToxinsBotulismCosmeticsFemaleHumansImmunologic FactorsInjectionsMiddle AgedTreatment OutcomeYoung AdultBotulinum AntitoxinBotulinum ToxinsCosmeticsImmunologic Factors

Identifiers

PMID30142749
PMCPMC6112997

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.