ArticleAmerican journal of physiology. Heart and circulatory physiology2018
Structural and functional cardiac profile after prolonged duration of mechanical unloading: potential implications for myocardial recovery.
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In one paragraph
Article in American journal of physiology. Heart and circulatory physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- Histone deacetylase 4: A therapeutic target for cardiovascular diseases (Review).International journal of molecular medicine · 2025Review
- Animal Models for Mechanical Circulatory Support: A Research Review.Reviews in cardiovascular medicine · 2024Review
- Circulating Myokines as Novel Biomarkers for Cardiovascular Diseases.Reviews in cardiovascular medicine · 2024Review
- Somatostatin receptors in fibrotic myocardium.PloS one · 2024Article
- Cardiac fibroblasts and mechanosensation in heart development, health and disease.Nature reviews. Cardiology · 2023Review
- Myocardial Recovery.Diagnostics (Basel, Switzerland) · 2023Review
- Cardiac mechanics and reverse remodelling under mechanical support from left ventricular assist devices.Frontiers in cardiovascular medicine · 2023Review
- Myostatin/AKT/FOXO Signaling Is Altered in Human Non-Ischemic Dilated Cardiomyopathy.Life (Basel, Switzerland) · 2022Article
- Mechanical Stretch Promotes Macrophage Polarization and Inflammation via the RhoA-ROCK/NF-BioMed research international · 2022Article
- What Means Fourth Industrial Revolution for Medicine.Maedica · 2021Article
- Reverse Remodeling With Left Ventricular Assist Devices.Circulation research · 2021Review
- Myostatin as a Biomarker of Muscle Wasting and other Pathologies-State of the Art and Knowledge Gaps.Nutrients · 2020Review
- Can Myocardium Regenerate?Maedica · 2020Article
- Activin type II receptor ligand signaling inhibition after experimental ischemic heart failure attenuates cardiac remodeling and prevents fibrosis.American journal of physiology. Heart and circulatory physiology · 2020Article
- Cardiac contractile dysfunction and protein kinase C-mediated myofilament phosphorylation in disease and aging.The Journal of general physiology · 2019Article
Corrections and comments
- Commented on by
Authors and funding
24 authors at 2 institutions in 2 countries.
Estibaliz CastilleroDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Ziad A AliDivision of Cardiology, College of Physicians and Surgeons of Columbia University , New York, New York.
Hirokazu AkashiDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Nicholas GiangrecoDepartment of Biomedical Informatics, Systems Biology, Institute for Genomic Medicine, Data Science Institute, Columbia University , New York, New York.
Catherine WangDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Eric J StöhrDivision of Cardiology, College of Physicians and Surgeons of Columbia University , New York, New York.
Ruping JiDivision of Cardiology, College of Physicians and Surgeons of Columbia University , New York, New York.
Xiaokan ZhangDivision of Cardiology, College of Physicians and Surgeons of Columbia University , New York, New York.
Nathaniel KheysinDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Joo-Eun S ParkDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Sheetal HegdeDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Sanatkumar PatelDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Samantha SteinDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Carlos CuencaDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Diana LeungDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Shunichi HommaDivision of Cardiology, College of Physicians and Surgeons of Columbia University , New York, New York.
Nicholas P TatonettiDepartment of Biomedical Informatics, Systems Biology, Institute for Genomic Medicine, Data Science Institute, Columbia University , New York, New York.
Veli K TopkaraDivision of Cardiology, College of Physicians and Surgeons of Columbia University , New York, New York.
Koji TakedaDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Paolo C ColomboDivision of Cardiology, College of Physicians and Surgeons of Columbia University , New York, New York.
Yoshifumi NakaDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
H Lee SweeneyDepartment of Pharmacology, University of Florida , Gainesville, Florida.
P Christian SchulzeDivision of Cardiology, College of Physicians and Surgeons of Columbia University , New York, New York.
Isaac GeorgeDivision of Cardiothoracic Surgery, College of Physicians and Surgeons of Columbia University , New York, New York.
Columbia University · USUniversity of Florida · US
Funding
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2MCardiac Lipotoxicity and Ceramide Metabolism in Heart FailureR01HL114813 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI COLOMBO, PAOLO C, SCHULZE, P. CHRISTIAN · 2013 to 2017
$3.0MNCATS NIH HHS UL1 TR000040NHLBI NIH HHS R01 HL114813
Abstract
Clinical and experimental studies have suggested that the duration of left ventricular assist device (LVAD) support may affect remodeling of the failing heart. We aimed to 1) characterize the changes in Ca
Indexed as
Heart-Assist DevicesVentricular Function, LeftApoptosisCalcium-Calmodulin-Dependent Protein Kinase Type 2Cardiomyopathy, DilatedCase-Control StudiesFemaleFibrosisHeart FailureHeart VentriclesHistone DeacetylasesHumansMaleMEF2 Transcription FactorsMiddle AgedMyocardiumCalcium-Calmodulin-Dependent Protein Kinase Type 2CAMK2D protein, humanHDAC4 protein, humanHistone DeacetylasesMEF2 Transcription FactorsMSTN protein, humanMyostatinRepressor ProteinsSmad2 ProteinSMAD2 protein, humanheart failureleft ventricular assist devicemechanical supportreverse remodeling
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What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.