Evidence map›Paper›PMID 30141983›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2018

Shear stress augments mitochondrial ATP generation that triggers ATP release and Ca

Kimiko Yamamoto, Hiromi Imamura, Joji Ando

Open access · hybridAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 85 citations in OpenAlex.

  1. Purine metabolic adaptation protects the endothelium from disturbed flow-induced DNA damage and atherosclerosis.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  5. Observational
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  7. Impact of Estrogen on Purinergic Signaling in Microvascular Disease.International journal of molecular sciences · 2025
    Review
  8. Microphysiological gut-on-chip enables extendedFrontiers in cellular and infection microbiology · 2025
    Article
  9. Article
  10. Integrating molecular and cellular components of endothelial shear stress mechanotransduction.American journal of physiology. Heart and circulatory physiology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Kimiko YamamotoLaboratory of System Physiology, Department of Biomedical Engineering, Graduate School of Medicine, University of Tokyo , Tokyo , Japan.
Hiromi ImamuraLaboratory of Functional Biology, Graduate School of Biostudies, Kyoto University , Kyoto , Japan.
Joji AndoLaboratory of Biomedical Engineering, School of Medicine, Dokkyo Medical University , Tochigi , Japan.
Dokkyo Medical University · JPKyoto University · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular endothelial cells (ECs) sense and transduce hemodynamic shear stress into intracellular biochemical signals, and Ca

Indexed as

Calcium SignalingMechanotransduction, CellularAdenosine TriphosphateBiosensing TechniquesCaveolaeCaveolin 1Cells, CulturedEndothelial CellsFluorescence Resonance Energy TransferHumansMitochondriaStress, MechanicalTime FactorsAdenosine TriphosphateCAV1 protein, humanCaveolin 1ATPcalcium signalingendothelial cellsmitochondriashear stress

Identifiers

PMID30141983
PMCPMC6297820
OpenAlexW2888323253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.