Evidence map›Paper›PMID 30141966›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Noncommunicable Respiratory Disease and Air Pollution Exposure in Malawi (CAPS). A Cross-Sectional Study.

Rebecca Nightingale, Maia Lesosky, Graham Flitz, Sarah J Rylance, Jamilah Meghji, Peter Burney, John Balmes, Kevin Mortimer

Open access · hybridAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 5 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 5 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  5. Chronic obstructive pulmonary disease in sub-Saharan Africa.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Pooled it
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  17. Prevalence and determinants of chronic respiratory diseases in adults in rural Sudan.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Rebecca Nightingale1 Liverpool School of Tropical Medicine, Liverpool, United Kingdom.ORCID 0000-0001-5636-8531
Maia Lesosky3 Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
Graham Flitz4 University of California, Berkeley, California.
Sarah J Rylance1 Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Jamilah Meghji1 Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Peter Burney5 National Heart and Lung Institute, Imperial College, London, United Kingdom; and.
John Balmes4 University of California, Berkeley, California.
Kevin Mortimer1 Liverpool School of Tropical Medicine, Liverpool, United Kingdom.ORCID 0000-0002-8118-8871
University of Liverpool · GBImperial College London · GBUniversity of California, Berkeley · USUniversity of California, San Francisco · USUniversity of Cape Town · ZA

Funding

Cluster Randomized Controlled Trial of an Advanced Stove to Reduce Risk of COPDR56ES023566 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BALMES, JOHN R · 2014 to 2014
$120k
Medical Research Council MR/K006533/1Medical Research Council MR/L002515/1Medical Research Council MR/P022006/1NIEHS NIH HHS R56 ES023566Wellcome TrustWellcome Trust 085790/Z/08/Z
6 · The paper itself

Abstract

rationaleNoncommunicable respiratory diseases and exposure to air pollution are thought to be important contributors to morbidity and mortality in sub-Saharan African adults.

objectivesWe set out to explore the prevalence and determinants of noncommunicable respiratory disease among adults living in Chikhwawa District, Malawi.

methodsWe performed a cross-sectional study among adults in communities participating in a randomized controlled trial of a cleaner-burning biomass-fueled cookstove intervention (CAPS [Cooking and Pneumonia Study]) in rural Malawi. We assessed chronic respiratory symptoms, spirometric abnormalities, and personal exposure to air pollution (particulate matter <2.5 μm in aerodynamic diameter [PM MEASUREMENTS AND MAIN

resultsOne thousand four hundred eighty-one participants (mean [SD] age, 43.8 [17.8] yr; 57% female) were recruited. The prevalence of chronic respiratory symptoms, spirometric obstruction, and restriction were 13.6% (95% confidence interval [CI], 11.9-15.4), 8.7% (95% CI, 7.0-10.7), and 34.8% (95% CI, 31.7-38.0), respectively. Median 48-hour personal PM

conclusionsThe burden of chronic respiratory symptoms, abnormal spirometry, and air pollution exposures in adults in rural Malawi is of considerable potential public health importance. We found little evidence that air pollution exposures were associated with chronic respiratory symptoms or spirometric abnormalities and no evidence that the CAPS intervention had effects on the secondary trial outcomes. More effective prevention and control strategies for noncommunicable respiratory disease in sub-Saharan Africa are needed. Clinical trial registered with www.isrctn.com (ISRCTN 59448623).

Indexed as

AdolescentAdultAgedAir PollutionCarbon MonoxideCross-Sectional StudiesFemaleHumansInhalation ExposureMalawiMaleMiddle AgedParticulate MatterPrevalenceRespiratory Tract DiseasesSpirometryCarbon MonoxideParticulate Matterchronic obstructive pulmonary diseaseCooking and Pneumonia Studycookstovehousehold air pollutionMalawi

Identifiers

PMID30141966
PMCPMC6396863
OpenAlexW2888252234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.