ArticleJournal of neurosurgery. Pediatrics2018
Treated hydrocephalus in individuals with myelomeningocele in the National Spina Bifida Patient Registry.
Article in Journal of neurosurgery. Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 55 citations in OpenAlex.
- Ventriculovesical shunting in pediatric hydrocephalus with neurogenic bladder: a salvage case series and biomechanical considerations.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- AI Model Integrating Imaging and Clinical Data for Predicting CSF Diversion in Neonatal Hydrocephalus: A Preliminary Study.Human brain mapping · 2025Article
- A global survey of neurosurgeons' awareness of neural tube defect prevalence, prevention strategies, and their clinical time allocation to spina bifida care.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Day-to-day variations and effects of urinary and fecal incontinence among adults with spina bifida: An ecological momentary assessment diary pilot study.Journal of pediatric urology · 2025Article
- Neurosurgical management of Myelomeningocele in premature infants: a case series.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Observational
- Accuracy in reporting incontinence in adults with spina bifida: A pilot study.Journal of pediatric urology · 2024Article
- Paediatric hydrocephalus.Nature reviews. Disease primers · 2024Review
- Association of maternal ABO blood type with lesion level and birthweight of children with spina bifida: a descriptive study.Journal of medicine and life · 2024Article
- Neurosurgical Management of Myelomeningocele in Premature Infants: A Case Series.Research square · 2024Article
- Current status and challenges of neurosurgical procedures for patients with myelomeningocele in real-world Japan.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- What has changed in pediatric neurosurgical care in spina bifida? A 30-year UAB/Children's of Alabama observational overview.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Hydrocephalus and school-age neurodevelopmental outcomes in the management of myelomeningocele prenatal surgery trial: a secondary analysis.Journal of neurosurgery. Pediatrics · 2023Article
- Article
- Impact of Spina Bifida on Sleep Quality: Current Insights.Nature and science of sleep · 2023Review
- Multidisciplinary spina bifida clinic: the Chicago experience.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Review
- Determination of anatomic level of myelomeningocele by prenatal ultrasound.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Neurosurgical procedures for children with myelomeningocele after fetal or postnatal surgery: a comparative effectiveness study.Developmental medicine and child neurology · 2021Article
- Postnatal Repair of Open Neural Tube Defects: A Single Center with 90-Month Interdisciplinary Follow-Up.Journal of clinical medicine · 2021Article
- Factors Associated with Timeliness of Surgical Repair among Infants with Myelomeningocele: California Perinatal Quality Care Collaborative, 2006 to 2011.American journal of perinatology · 2020Observational
- Abnormal anisotropic diffusion properties in pediatric myelomeningocele patients treated with fetal surgery: an initial DTI study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
Corrections and comments
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Authors and funding
13 authors at 8 institutions in 1 country.
Funding
Abstract
OBJECTIVEAlthough the majority of patients with myelomeningocele have hydrocephalus, reported rates of hydrocephalus treatment vary widely. The purpose of this study was to determine the rate of surgical treatment for hydrocephalus in patients with myelomeningocele in the National Spina Bifida Patient Registry (NSBPR). In addition, the authors explored the variation in shunting rates across NSBPR institutions, examined the relationship between hydrocephalus, and the functional lesion level of the myelomeningocele, and evaluated for temporal trends in rates of treated hydrocephalus.METHODSThe authors queried the NSBPR to identify all patients with myelomeningoceles. Individuals were identified as having been treated for hydrocephalus if they had undergone at least 1 hydrocephalus-related operation. For each participating NSBPR institution, the authors calculated the proportion of patients with treated hydrocephalus who were enrolled at that site. Logistic regression was performed to analyze the relationship between hydrocephalus and the functional lesion level of the myelomeningocele and to compare the rate of treated hydrocephalus in children born before 2005 with those born in 2005 or later.RESULTSA total of 4448 patients with myelomeningocele were identified from 26 institutions, of whom 3558 patients (79.99%) had undergone at least 1 hydrocephalus-related operation. The rate of treated hydrocephalus ranged from 72% to 96% among institutions enrolling more than 10 patients. This difference in treatment rates between centers was statistically significant (p < 0.001). Insufficient data were available in the NSBPR to analyze reasons for the different rates of hydrocephalus treatment between sites. Multivariate logistic regression demonstrated that more rostral functional lesion levels were associated with higher rates of treated hydrocephalus (p < 0.001) but demonstrated no significant difference in hydrocephalus treatment rates between children born before versus after 2005.CONCLUSIONSThe rate of hydrocephalus treatment in patients with myelomeningocele in the NSBPR is 79.99%, which is consistent with the rates in previously published literature. The authors' data demonstrate a clear association between functional lesion level of the myelomeningocele and the need for hydrocephalus treatment.
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