ArticleProgress in biomaterials2018
Tailoring the gelatin/chitosan electrospun scaffold for application in skin tissue engineering: an in vitro study.
Article in Progress in biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Characterization of Hydrogels of Gelatin/O-Carboxymethyl Chitosan in Ovule Form with Curcumin and Retinyl Palmitate as a Treatment for Cervical Cancer.Gels (Basel, Switzerland) · 2026Article
- A novel cycloastragenol-encapsulated carboxymethyl chitosan-silk fibroin hydrogel combined with sucralfate alleviates MNNG-induced chronic atrophic gastritis by targeting HIF-1α and VEGF signaling pathways.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Valorization ofRSC advances · 2025Article
- Melatonin/Chitosan Biomaterials for Wound Healing and Beyond: A Multifunctional Therapeutic Approach.International journal of molecular sciences · 2025Review
- Advances in drug delivery systems for the management of gout and hyperuricemia.Frontiers in pharmacology · 2025Review
- Honey-Based Sodium Alginate-Polyvinyl Alcohol Hydrogel Containing Green-Synthesized Chitosan-Zinc Oxide Nanoparticles for Wound Healing.Bioinorganic chemistry and applications · 2025Article
- Chitosan-Peptide Composites for Tissue Engineering Applications: Advances in Treatment Strategies.Current protein & peptide science · 2025Review
- Advances in arthropod-inspired bionic materials for wound healing.Materials today. Bio · 2024Review
- 3D-Printed Polycaprolactone-Based Containing Calcium Zirconium Silicate: Bioactive Scaffold for Accelerating Bone Regeneration.Polymers · 2024Article
- Article
- Nanomaterials-incorporated hydrogels for 3D bioprinting technology.Nano convergence · 2023Review
- Detection of Limbal Stem Cells Adhered to Melt Electrospun Silk Fibroin and Gelatin-Modified Polylactic Acid Scaffolds.Polymers · 2023Article
- Development of Scaffolds from Bio-Based Natural Materials for Tissue Regeneration Applications: A Review.Gels (Basel, Switzerland) · 2023Review
- Biomaterials Based on Chitosan and Its Derivatives and Their Potential in Tissue Engineering and Other Biomedical Applications-A Review.Molecules (Basel, Switzerland) · 2022Review
- Recent Advances of Chitosan Formulations in Biomedical Applications.International journal of molecular sciences · 2022Review
- Cell loaded hydrogel containing Ag-doped bioactive glass-ceramic nanoparticles as skin substitute: Antibacterial properties, immune response, and scarless cutaneous wound regeneration.Bioengineering & translational medicine · 2022Article
- A Novel Method of Endotoxins Removal from Chitosan Hydrogel as a Potential Bioink Component Obtained by COInternational journal of molecular sciences · 2022Article
- State-of-the-Art Review of Electrospun Gelatin-Based Nanofiber Dressings for Wound Healing Applications.Nanomaterials (Basel, Switzerland) · 2022Review
- Review
- Fabrication andCell journal · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The nanofibrous structure containing protein and polysaccharide has good potential in tissue engineering. The present work aims to study the role of chitosan in gelatin/chitosan nanofibrous scaffolds fabricated through electrospinning process under optimized condition. The performance of chitosan in gelatin/chitosan nanofibrous scaffolds was evaluated by mechanical tests, scanning electron microscopy (SEM), Fourier transform infrared (FTIR) and in vitro cell culture on scaffolds with different gelatin/chitosan blend ratios. To assay the influence of chitosan ratio on biocompatibility of the electrospun gelatin/chitosan scaffolds for skin tissue engineering, the culturing of the human dermal fibroblast cells (HDF) on nanofibers in terms of attachment, morphology and proliferation was evaluated. Morphological observation showed that HDF cells were attached and spread well on highly porous gelatin/chitosan nanofibrous scaffolds displaying spindle-like shapes and stretching. The fibrous morphologies of electrospun gelatin/chitosan scaffolds in culture medium were maintained during 7 days. Cell proliferation on electrospun gelatin/chitosan scaffolds was quantified by MTS assay, which revealed the positive effect of chitosan content (around 30%) as well as the nanofibrous structure on the biocompatibility (cell proliferation and attachment) of substrates.
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