Evidence map›Paper›PMID 30140937›Full record

ArticleClinical neuroradiology2019

Cervical MRI Rating Scale: Innovative Approach to Differentiate between Demyelinating and Disc Lesions.

Uri Givon, Chen Hoffman, Alon Friedlander, Anat Achiron

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in Clinical neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Uri GivonMultiple Sclerosis Center, Sheba Medical Center, Tel Hashomer, Israel. ugivon@zahav.net.il.ORCID http://orcid.org/0000-0002-6502-6661
Chen HoffmanImaging Division, Sheba Medical Center, Tel Hashomer, Israel.
Alon FriedlanderOrthopedic Division, Sheba Medical Center, Tel Hashomer, Israel.
Anat AchironMultiple Sclerosis Center, Sheba Medical Center, Tel Hashomer, Israel.ORCID http://orcid.org/0000-0002-2020-3126
Tel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe difficult differentiation between multiple sclerosis (MS) lesions and cervical spondylotic myelopathy (CSM) in the cervical spine is well known. The magnetic resonance imaging (MRI) appearance of both lesions is similar, and clinical parameters are usually used for diagnosis. The objective was to establish a reliable radiologic paradigm for diagnosis of demyelinating lesions in the cervical spine.

methodsThe MRI studies of 33 patients with MS (42 lesions) and 55 patients with CSM (60 lesions) were obtained. Lesions were evaluated for vertebral level, lesion location and size in the sagittal and axial planes, cord thickness, well-defined or ill-defined borders, presence of edema and enhancement with gadolinium. Significant differences were used to create a paradigm, which was used for the evaluation of a different group of 32 MRIs with 42 concomitant MS and CSM lesions.

resultsSignificant differences were seen in the level, location within the cord in both planes, lesion size, cord thickness and lesion border. The MS lesions were well-defined lesions found in C1-3, posterior in the sagittal plane, central in the axial plane, with a normal or increased cord thickness. Good agreement was seen in the validation stage.

conclusionThe new CSM-MS lesion score allows accurate diagnosis of demyelinating lesions in the cervical spine vs. CSM lesions.

Indexed as

AdultCervical VertebraeContrast MediaDemyelinating DiseasesDiagnosis, DifferentialFemaleGadoliniumHumansMagnetic Resonance ImagingMaleMiddle AgedMultiple SclerosisReproducibility of ResultsRetrospective StudiesSpinal Cord DiseasesSpondylosisContrast MediaGadoliniumChronic spondylotic myelopathyDemyelinating lesionsDifferential diagnosisMRIMultiple sclerosis

Identifiers

PMID30140937
OpenAlexW2888446283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.