Evidence map›Paper›PMID 30140912›Full record

Trial reportJAMA dermatology2018

Aprepitant for the Treatment of Pruritus in Sézary Syndrome: A Randomized Crossover Clinical Trial.

John A Zic, Brittany T Straka, Laura Y McGirt, Hui Nian, Chang Yu, Nancy J Brown

Open access · bronzeAbstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in JAMA dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. What's New in Cutaneous T-Cell Lymphoma-Associated Pruritus.American journal of clinical dermatology · 2024
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

John A ZicDepartment of Dermatology, Vanderbilt University Medical Center, Nashville, Tennessee.
Brittany T StrakaDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Laura Y McGirtDivision of Dermatology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Hui NianDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee.
Chang YuDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee.
Nancy J BrownDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Vanderbilt University Medical Center · USCarolinas Medical Center · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
NCATS NIH HHS UL1 TR000445NCI NIH HHS K12 CA090625
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAprepitantCross-Over StudiesDouble-Blind MethodFemaleHumansMaleMiddle AgedNeurokinin-1 Receptor AntagonistsPruritusSezary SyndromeSkin NeoplasmsTreatment FailureAprepitantNeurokinin-1 Receptor Antagonists

Identifiers

PMID30140912
PMCPMC6233739
OpenAlexW2888346002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.