ReviewAnimal nutrition (Zhongguo xu mu shou yi xue hui)2018
Potential and challenges of tannins as an alternative to in-feed antibiotics for farm animal production.
Review in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 195 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
195 citing papers in PubMed, 1 synthesis or guideline pooled it, 527 citations in OpenAlex.
- Meta-analysis of the effects of on-farm management strategies on milk yields of dairy cattle on smallholder farms in the Tropics.Animal : an international journal of animal bioscience · 2020Pooled it
- Tannic acid as a multi-target regulator of intestinal barrier function in livestock.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Review
- Chestnut-quebracho tannins shape the fecal metabolome of weaned pigs through microbiota-dependent urolithin production.Journal of animal science and biotechnology · 2026Article
- Effects of chestnut tannin and in combination with quebracho tannin on early-weaned piglets.Veterinary and animal science · 2026Article
- Neem tree foliage as a substitute for Rhodes grass hay: effects on ruminal fermentation, intake, and digestibility in dry cows.Tropical animal health and production · 2026Article
- Effects of Different Commercial Formulations of Tannic Acid Added at an Equal Inclusion Rate on Intestinal Health and Microbial Flora in Yellow-Feathered Broilers.Animals : an open access journal from MDPI · 2026Article
- Dietary gallic acid supplementation alleviates LPS-induced inflammatory responses and intestinal barrier damage in chickens at an early age.Poultry science · 2026Article
- Combined ethanolic extracts ofVeterinary world · 2026Article
- Metagenomic insights into the global wild boar faecal microbiome reveal novel taxa and carbohydrate degraders distinguishing wild and domesticated Sus.Microbiome · 2026Article
- The Effects of Adding Walnut Green Husk on the Quality of Alfalfa Mixed Silage, Protein Degradation, Microbial Community, and Their Interrelationships.Metabolites · 2026Article
- Tannins in reducing diarrhoea incidence and methane emissions from a long-term perspective in dairy calves.Veterinary research communications · 2026Review
- Influence of mimosa (Acacia mearnsii) tannin encapsulated with sunflower oil on rumen fermentation, methane and in vitro organic matter digestibility.Scientific reports · 2026Article
- Insights into Non-Antibiotic Alternative and Emerging Control Strategies for Chicken Coccidiosis.Animals : an open access journal from MDPI · 2026Review
- Article
- Effects ofArchives animal breeding · 2026Article
- The efficacy of kenaf leaf meal on the apparent nutrient digestibility and physiological parameters of New Zealand white rabbit bucks.Translational animal science · 2026Article
- Duckweed (Aquaculture nutrition · 2026Article
- Review
- Formal and informal antimicrobial trade and usage in farmed animals of the urban area of Lomé, Togo.One health (Amsterdam, Netherlands) · 2025Article
- Condensed Tannins in Drinking Water for Broilers and Their Effects on Intestinal Micrometry, Performance, and Fatty Acid Profile in Meat.Veterinary sciences · 2025Article
135 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Naturally occurring plant compounds including tannins, saponins and essential oils are extensively assessed as natural alternatives to in-feed antibiotics. Tannins are a group of polyphenolic compounds that are widely present in plant region and possess various biological activities including antimicrobial, anti-parasitic, anti-viral, antioxidant, anti-inflammatory, immunomodulation, etc. Therefore, tannins are the major research subject in developing natural alternative to in-feed antibiotics. Strong protein affinity is the well-recognized property of plant tannins, which has successfully been applied to ruminant nutrition to decrease protein degradation in the rumen, and thereby improve protein utilization and animal production efficiency. Incorporations of tannin-containing forage in ruminant diets to control animal pasture bloat, intestinal parasite and pathogenic bacteria load are another 3 important applications of tannins in ruminant animals. Tannins have traditionally been regarded as "anti-nutritional factor" for monogastric animals and poultry, but recent researches have revealed some of them, when applied in appropriate manner, improved intestinal microbial ecosystem, enhanced gut health and hence increased productive performance. The applicability of plant tannins as an alternative to in-feed antibiotics depends on many factors that contribute to the great variability in their observed efficacies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.