Evidence map›Paper›PMID 30140752›Full record

ReviewAnimal nutrition (Zhongguo xu mu shou yi xue hui)2018

Essential oils as alternatives to antibiotics in swine production.

Faith A Omonijo, Liju Ni, Joshua Gong, Qi Wang, Ludovic Lahaye, Chengbo Yang

Open access · goldAbstract readReview
In one paragraph

Review in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed
24.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 292 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Mitigating Effects ofAnimals : an open access journal from MDPI · 2025
    Article
  13. Article
  14. Effective Control ofAntibiotics (Basel, Switzerland) · 2025
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Faith A OmonijoDepartment of Animal Science, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Liju NiDepartment of Animal Science, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Joshua GongGuelph Food Research Centre, Agriculture and Agri-Food Canada, Guelph, ON N1G 5C9, Canada.
Qi WangGuelph Food Research Centre, Agriculture and Agri-Food Canada, Guelph, ON N1G 5C9, Canada.
Ludovic LahayeJefo Nutrition Inc., Saint-Hyacinthe, QC J2S 7B6, Canada.
Chengbo YangDepartment of Animal Science, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
University of Manitoba · CAAgriculture and Agri-Food Canada · CACegep de Saint Hyacinthe · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review article summarizes the efficacy, feasibility and potential mechanisms of the application of essential oils as antibiotic alternatives in swine production. Although there are numerous studies demonstrating that essential oils have several properties, such as antimicrobial, antioxidative and anti-inflammatory effects, feed palatability enhancement and improvement in gut growth and health, there is still a need of further investigations to elucidate the mechanisms underlying their functions. In the past, the results has been inconsistent in both laboratory and field studies because of the varied product compositions, dosages, purities and growing stages and conditions of animals. The minimal inhibitory concentration (MIC) of essential oils needed for killing enteric pathogens may not ensure the optimal feed intake and the essential oils inclusion cost may be too high in swine production. With the lipophilic and volatile nature of essential oils, there is a challenge in effective delivery of essential oils within pig gut and this challenge can partially be resolved by microencapsulation and nanotechnology. The effects of essential oils on inflammation, oxidative stress, microbiome, gut chemosensing and bacterial quorum sensing (QS) have led to better production performance of animals fed essential oils in a number of studies. It has been demonstrated that essential oils have good potential as antibiotic alternatives in feeds for swine production. The combination of different essential oils and other compounds (synergistic effect) such as organic acids seems to be a promising approach to improve the efficacy and safety of essential oils in applications. High-throughput systems technologies have been developed recently, which will allow us to dissect the mechanisms underlying the functions of essential oils and facilitate the use of essential oils in swine production.

Indexed as

Essential oilsInflammationMedium chain fatty acidsOrganic acidsOxidative stressPigs

Identifiers

PMID30140752
PMCPMC6104524
OpenAlexW2757268196

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.