Evidence map›Paper›PMID 30140745›Full record

ArticleScience advances2018

An ultraweak interaction in the intrinsically disordered replication machinery is essential for measles virus function.

Sigrid Milles, Malene Ringkjøbing Jensen, Carine Lazert, Serafima Guseva, Stefaniia Ivashchenko, Guillaume Communie, Damien Maurin, Denis Gerlier, Rob W H Ruigrok, Martin Blackledge

Abstract read
In one paragraph

Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Negative and ambisense RNA virus ribonucleocapsids: more than protective armor.Microbiology and molecular biology reviews : MMBR · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sigrid MillesUniversité Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Biologie Structurale, 38000 Grenoble, France.ORCID 0000-0001-9362-9606
Malene Ringkjøbing JensenUniversité Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Biologie Structurale, 38000 Grenoble, France.
Carine LazertInternational Center for Infectiology Research, INSERM, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université de Lyon, Lyon, France.
Serafima GusevaUniversité Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Biologie Structurale, 38000 Grenoble, France.
Stefaniia IvashchenkoUniversité Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Biologie Structurale, 38000 Grenoble, France.
Guillaume CommunieUniversité Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Biologie Structurale, 38000 Grenoble, France.
Damien MaurinUniversité Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Biologie Structurale, 38000 Grenoble, France.
Denis GerlierInternational Center for Infectiology Research, INSERM, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université de Lyon, Lyon, France.
Rob W H RuigrokUniversité Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Biologie Structurale, 38000 Grenoble, France.ORCID 0000-0002-8094-6642
Martin BlackledgeUniversité Grenoble Alpes, CNRS, Commissariat à l'Energie Atomique et aux Energies Alternatives, Institut de Biologie Structurale, 38000 Grenoble, France.ORCID 0000-0003-0935-721X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measles virus genome encapsidation is essential for viral replication and is controlled by the intrinsically disordered phosphoprotein (P) maintaining the nucleoprotein in a monomeric form (N) before nucleocapsid assembly. All paramyxoviruses harbor highly disordered amino-terminal domains (P

Indexed as

Virus ReplicationAmino Acid SequenceHumansIntrinsically Disordered ProteinsMeaslesMeasles virusModels, MolecularNucleocapsid ProteinsNucleoproteinsPhosphoproteinsProtein BindingProtein ConformationSequence HomologyViral ProteinsX-Ray DiffractionIntrinsically Disordered ProteinsNucleocapsid Proteinsnucleoprotein, Measles virusNucleoproteinsPhosphoproteinsViral Proteins

Identifiers

PMID30140745
PMCPMC6105297

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.