Evidence map›Paper›PMID 30140708›Full record

ArticleJournal of immunology research2018

NF-

Jie Yu, Mingqiang Hua, Xueyun Zhao, Rui Wang, Chaoqing Zhong, Chen Zhang, Ruiqing Wang, Guosheng Li, Na He, Ming Hou and 1 more

Abstract read
In one paragraph

Article in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Novel Biomarkers for Diagnosis and Monitoring of Immune Thrombocytopenia.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jie YuDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Mingqiang HuaDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Xueyun ZhaoDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Rui WangDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Chaoqing ZhongDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Chen ZhangDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Ruiqing WangDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Guosheng LiDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Na HeDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Ming HouDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Daoxin MaDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.ORCID 0000-0003-0664-8441

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe NLRP3 inflammasome plays important roles in the pathogenesis of autoimmune diseases. However, the role of the NLRP3 inflammasome in the pathophysiology of immune thrombocytopenia (ITP) remains unclear.

methodsRT-PCR was used to examine the polymorphism and expression of genes involved in the NLRP3 inflammasome in ITP patients. T helper cells and apoptosis of PBMC from ITP patients were analyzed by flow cytometry. The antiplatelet autoantibodies in plasma were determined by modified monoclonal antibody-specific immobilization of platelet antigens (MAIPA).

resultsWe found that the NF-

conclusionThe NF-

Indexed as

GenotypeAdolescentAdultAgedAged, 80 and overAutoantibodiesBiomarkersFemaleGene DosageGenetic Predisposition to DiseaseHumansINDEL MutationInflammasomesMaleMiddle AgedMolecular Targeted TherapyAutoantibodiesBiomarkersInflammasomesNF-kappa BNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanPlatelet Aggregation Inhibitors

Identifiers

PMID30140708
PMCPMC6081577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.