Evidence map›Paper›PMID 30140700›Full record

ArticleBioMed research international2018

Alpha-Tocopherol Serum Levels Are Increased in Caucasian Women with Uterine Fibroids: A Pilot Study.

Michał Ciebiera, Jolanta Szymańska-Majchrzak, Aleksandra Sentkowska, Krzysztof Kilian, Zbigniew Rogulski, Grażyna Nowicka, Grzegorz Jakiel, Piotr Tomaszewski, Marta Włodarczyk

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  11. Non-hormonal mediators of uterine fibroid growth.Current opinion in obstetrics & gynecology · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Michał CiebieraFirst Department of Obstetrics and Gynecology, Centre of Postgraduate Medical Education, Ul. Czerniakowska 231, 00-416 Warsaw, Poland.ORCID 0000-0001-5780-5983
Jolanta Szymańska-MajchrzakDepartment of Biochemistry, Medical University of Warsaw, Ul. Banacha 1b, 02-093 Warsaw, Poland.
Aleksandra SentkowskaHeavy Ion Laboratory, University of Warsaw, Ul. Pasteura 5a, 02-093 Warsaw, Poland.
Krzysztof KilianHeavy Ion Laboratory, University of Warsaw, Ul. Pasteura 5a, 02-093 Warsaw, Poland.
Zbigniew RogulskiRadiochemistry for Medicine and Industry, Biological and Chemical Research Centre, University of Warsaw, Ul. Żwirki i Wigury 101, 02-089 Warsaw, Poland.
Grażyna NowickaDepartment of Biochemistry and Pharmacogenomics, Medical University of Warsaw, Ul. Banacha 1b, 02-093 Warsaw, Poland.
Grzegorz JakielFirst Department of Obstetrics and Gynecology, Centre of Postgraduate Medical Education, Ul. Czerniakowska 231, 00-416 Warsaw, Poland.
Piotr TomaszewskiDepartment of Biochemistry, Second Faculty of Medicine, Medical University of Warsaw, Warsaw Poland, Ul. Banacha 1, 02-097 Warsaw, Poland.
Marta WłodarczykDepartment of Biochemistry and Pharmacogenomics, Medical University of Warsaw, Ul. Banacha 1b, 02-093 Warsaw, Poland.
Medical University of Warsaw · PLUniversity of Warsaw · PLPostgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterine fibroids (UFs) are benign tumors of the reproductive tract, arising from smooth muscle cells of the uterus. Steroid hormones, estrogen, and progesterone are considered to be the most important links in the pathophysiology of UFs. Alpha-tocopherol (AT) is the most active form of vitamin E. What is important as far as UFs are concerned is that ATs contain structural determinants, which makes them possible ligands for estrogen receptors (ERs). We present a retrospective cohort study performed in a university teaching hospital. We included a total of 162 patients divided into 2 groups: with UFs and controls. The effects of age, body mass index (BMI), positive medical history, parity, and AT serum concentrations on the risk for the development of UFs were investigated. Mean AT serum concentrations were 11.66 ± 4.97

Indexed as

Adultalpha-TocopherolCohort StudiesFemaleHumansLeiomyomaMiddle AgedPilot ProjectsPolandRetrospective StudiesUterine Neoplasmsalpha-Tocopherol

Identifiers

PMID30140700
PMCPMC6081575
OpenAlexW2884882151

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.