Evidence map›Paper›PMID 30140694›Full record

ArticleBioMed research international2018

Cytotoxic and Apoptotic Effects of Govaniadine Isolated from

Nivethika Sivakumaran, Sameera R Samarakoon, Achyut Adhikari, Meran K Ediriweera, Kamani H Tennekoon, Neelika Malavige, Ira Thabrew, Ram Lal Swagat Shrestha

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Nivethika SivakumaranInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90 Cumaratunga Munidasa Mawatha, Colombo, Sri Lanka.
Sameera R SamarakoonInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90 Cumaratunga Munidasa Mawatha, Colombo, Sri Lanka.ORCID 0000-0002-5278-4770
Achyut AdhikariCentral Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal.ORCID 0000-0002-1065-5727
Meran K EdiriweeraInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90 Cumaratunga Munidasa Mawatha, Colombo, Sri Lanka.ORCID 0000-0001-9393-9516
Kamani H TennekoonInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90 Cumaratunga Munidasa Mawatha, Colombo, Sri Lanka.ORCID 0000-0003-0608-4340
Neelika MalavigeDepartment of Microbiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Ira ThabrewInstitute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, 90 Cumaratunga Munidasa Mawatha, Colombo, Sri Lanka.ORCID 0000-0002-8294-2071
Ram Lal Swagat ShresthaDepartment of Chemistry, Tribhuvan University, Amrit Science Campus, Kathmandu, Nepal.
University of Colombo · LKTribhuvan University · NPUniversity of Sri Jayewardenepura · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current breast cancer therapies have limitations in terms of increased drug resistance resulting in short-term efficacy, thus demanding the discovery of new therapeutic agents. In this study, cytotoxic activity and apoptotic effects of govaniadine isolated from

Indexed as

AlkaloidsApoptosisBreast NeoplasmsCorydalisHumansMCF-7 CellsReactive Oxygen SpeciesTerpenesAlkaloidsgovaniadineReactive Oxygen SpeciesTerpenes

Identifiers

PMID30140694
PMCPMC6081593
OpenAlexW2883810437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.