Evidence map›Paper›PMID 30140618›Full record

ArticleQuantitative imaging in medicine and surgery2018

Low-to-high b value DWI ratio approaches in multiparametric MRI of the prostate: feasibility, optimal combination of b values, and comparison with ADC maps for the visual presentation of prostate cancer.

Yin Xi, Alexander Liu, Franklin Olumba, Parker Lawson, Daniel N Costa, Qing Yuan, Gaurav Khatri, Takeshi Yokoo, Ivan Pedrosa, Robert E Lenkinski

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Article in Quantitative imaging in medicine and surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

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11citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Image Quality and Diagnostic Performance of Accelerated T2-weighted Imaging of Prostate with Deep Learning Reconstruction: A Comparative Study.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026
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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yin XiDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
Alexander LiuMedical School, UT Southwestern Medical Center, Dallas, TX, USA.
Franklin OlumbaMedical School, UT Southwestern Medical Center, Dallas, TX, USA.
Parker LawsonMedical School, UT Southwestern Medical Center, Dallas, TX, USA.
Daniel N CostaDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
Qing YuanDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
Gaurav KhatriDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
Takeshi YokooDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
Ivan PedrosaDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.
Robert E LenkinskiDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiffusion-weighted imaging (DWI) is considered by experts as one of the key elements in multi-parametric magnetic resonance imaging (mpMRI) employed in oncological studies outside the brain. A low-to-high b value ratio DWI has been proposed as an approach to decrease acquisition time and simplify the analysis of DWI data without the need to use a mathematical model.

methodsForty-three men with biopsy-proven prostate cancer (PCa) who underwent mpMRI of the prostate were included. Apparent diffusion coefficient (ADC) maps were created in the MRI scanner using a mono-exponential algorithm [b value (× number of averages) =0 (×1), 10 (×1), 25 (×1), 50 (×1), 100 (×1), 250 (×1), 450 (×1), 1,000 (×2), 1,500 (×3), and 2,000 (×5) s/mm

resultsQuantitative analysis shows DWI ratio images were not inferior to ADC maps quantitatively [P=0.0298 (ADC

conclusionsWe presented an analytical method for searching for the optimal combination of high and low b values for DWI ratio images in terms of minimizing CNR between cancer and surrounding benign tissues. Optimized DWI ratio images are comparable both quantitatively and qualitatively to ADC maps for the interpretation of DWI data in the context of prostate mpMRI.

Indexed as

apparent diffusion coefficient (ADC)Diffusion-weighted imaging ratio image (DWI ratio image)multi-parametric magnetic resonance imaging (mpMRI)optimal b valuesprostate cancer (PCa)

Identifiers

PMID30140618
PMCPMC6081353

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