ArticleTropical diseases, travel medicine and vaccines2018
Imported scrub typhus: first case in South America and review of the literature.
Article in Tropical diseases, travel medicine and vaccines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Molecular Epidemiology and Genetic Diversity of Orientia tsutsugamushi From Patients and Small Mammals in Xiangyun County, Yunnan Province, China.Veterinary medicine and science · 2025Article
- Article
- Development of a New Genus-Specific Quantitative Real-Time PCR Assay for the Diagnosis of Scrub Typhus in South America.Frontiers in medicine · 2022Article
- Orientia tsutsugamushi modulates cellular levels of NF-κB inhibitor p105.PLoS neglected tropical diseases · 2021Article
- International Rickettsia Disease Surveillance: An Example of Cooperative Research to Increase Laboratory Capability and Capacity for Risk Assessment of Rickettsial Outbreaks Worldwide.Frontiers in medicine · 2021Review
- Molecular Description of a Novel Orientia Species Causing Scrub Typhus in Chile.Emerging infectious diseases · 2020Article
- Diagnosis of severe scrub typhus infection by next-generation sequencing:a case report.BMC infectious diseases · 2020Article
- Scrub Typhus: Historic Perspective and Current Status of the Worldwide Presence ofTropical medicine and infectious disease · 2020Review
- Complex Cytokine Responses in Imported Scrub Typhus Cases, Germany, 2010-2018.The American journal of tropical medicine and hygiene · 2020Article
- The Eschar Size and Early Inoculation Lesion of Tsutsugamushi Disease on Jeju Island, Korea.Infection & chemotherapy · 2019Article
- Scrub Typhus in Continental Chile, 2016-2018Emerging infectious diseases · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundScrub typhus is a neglected vector-borne zoonosis causing life-threatening illnesses, endemic in the Asian-Pacific region and, as recently discovered, in southern Chile. Scrub typhus is rarely reported in travelers, most probably due to the lack of clinical experience and diagnostic tests in non-endemic countries. We report the first case of imported scrub typhus in South America. CASE PRESENTATION: A 62-year-old tourist from South Korea presented severely ill with fever, rash, and eschar in Santiago, Chile. Laboratory exams showed thrombocytopenia and elevated inflammation parameters, hepatic enzymes, and LDH. With the clinical suspicion of scrub typhus, empirical treatment with doxycycline was initiated and the patient recovered rapidly and without complications. The diagnosis was confirmed by IgM serology and by real-time PCR, which demonstrated infection with
conclusionsOnly due to the emerging clinical experience with endemic South American scrub typhus and the recent implementation of appropriate diagnostic techniques in Chile, were we able to firstly identify and adequately manage a severe case of imported scrub typhus in South America. Physicians attending febrile travelers need to be aware of this rickettsiosis, since it requires prompt treatment with doxycycline to avoid complications.
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