ArticleSAGE open medicine2018
The predictive factors of primary head and neck cancer stage at presentation and survival in a developing nation's tertiary hospital.
Article in SAGE open medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Machine learning for survival outcome in head and neck squamous cell carcinoma: a multicenter validation study.Scientific reports · 2025Observational
- The association between the mental health disorders, substance abuse, and tobacco use with head & neck cancer stage at diagnosis.Cancer causes & control : CCC · 2025Article
- Disparities in stage at diagnosis of head and neck tumours in Brazil: a comprehensive analysis of hospital-based cancer registries.Lancet regional health. Americas · 2025Article
- Ten-year (2009-2019) epidemiological study of head and neck, salivary glands and upper aerodigestive tract cancers, and overall survival outcomes in the Northern Territory of Australia.BMJ public health · 2024Article
- Esophageal and Head and Neck Cancer Patients Attending Ocean Road Cancer Institute in Tanzania from 2019 to 2021: An Observational Study.International journal of environmental research and public health · 2023Observational
- Otolaryngology needs among an adult homeless population: a prospective study.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2020Article
- Response Rate of Cisplatin Plus Docetaxel as Primary Treatment in Locally Advanced Head and Neck Carcinoma (Squamous Cell Types).Asian Pacific journal of cancer prevention : APJCP · 2020Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStage of head and neck cancers at presentation is a strong determinant of outcomes.
objectiveTo evaluate predictors of stage of head and neck cancers at presentation and survival in a Nigerian tertiary hospital. PATIENTS AND
methodsHealth records that met the inclusion criteria for head and neck cancers were retrieved using the International Classification of Diseases, 10th revision and analyzed with associations between variables modeled using logistic regression analysis.
resultsFrom a record of 487 head and neck neoplasms, 129 (26.5%) were malignant of which 122 health records met the criteria for analysis consisting of 83 (68.0%) males and 39 (32.0%) females aged 13-85 years (mean = 51 years; standard deviation = ±16 years). Alcohol (odds ratio = 1.99; 95% confidence interval = 1.08-3.69; p = 0.02) and tobacco exposure (odds ratio = 3.07; 95% confidence interval = 1.32-7.16; p = 0.01) were associated with increased odds for advanced tumor stage at presentation. Stage IV cancer (hazard ratio = 1.44; 95% confidence interval = 1.80-2.59), alcohol (hazard ratio = 2.19; 95% confidence interval = 1.18-4.10) and tobacco use (hazard ratio = 3.40; 95% confidence interval = 1.22-8.74) were associated with increased hazards for death.
conclusionAlcohol, tobacco use and smoke from cooking wood are predictive factors for advanced HNC stage at presentation. Stage IV cancer, alcohol and tobacco use were associated with an increased hazard for death.
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