Evidence map›Paper›PMID 30140376›Full record

ArticleOncotarget2018

STK405759 as a combination therapy with bortezomib or dexamethasone, in

Gabriela Rozic, Lena Paukov, Ziv Cohen, Irit Shapira, Adrian Duek, Ohad Bejamini, Abraham Avigdor, Arnon Nagler, Igor Koman, Merav Leiba

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Gabriela RozicAriel University, Ariel, Israel.
Lena PaukovDivision of Hematology and BMT, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Ziv CohenDivision of Hematology and BMT, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Irit ShapiraAriel University, Ariel, Israel.
Adrian DuekDivision of Hematology and BMT, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Ohad BejaminiDivision of Hematology and BMT, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Abraham AvigdorDivision of Hematology and BMT, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Arnon NaglerDivision of Hematology and BMT, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Igor KomanAriel University, Ariel, Israel.
Merav LeibaDivision of Hematology, Assuta, Ashdod University Hospital, Faculty of Health Sciences, Ben Gurion University of the Negev, Beersheba, Israel.
Sheba Medical Center · ILAriel University · ILBen-Gurion University of the Negev · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) remains an incurable hematological malignancy. Combination regimens of conventional and novel drugs have improved patient's survival. However, most patients inevitably relapse and become refractory to the current therapeutic armamentarium. We investigated the efficacy of combining the microtubule-targeting agent STK405759 with dexamethasone or bortezomib

Indexed as

bortezomibdexamethasonemultiple myelomaSTK405759survival

Identifiers

PMID30140376
PMCPMC6101139
OpenAlexW2887495422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.