Evidence map›Paper›PMID 30140362›Full record

ArticleOxidative medicine and cellular longevity2018

Influence of Dental Restorations on Oxidative Stress in Gingival Crevicular Fluid.

Ervin Taso, Vladimir Stefanovic, Ivana Stevanovic, Danilo Vojvodic, Aleksandra Topic, Aleksandra Petkovic-Curcin, Kosovka Obradovic-Djuricic, Aleksa Markovic, Mirjana Djukic, Dragana Vujanovic

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ervin TasoClinic for Stomatology, Military Medical Academy, Belgrade, Serbia.
Vladimir StefanovicClinic for Stomatology, Military Medical Academy, Belgrade, Serbia.
Ivana StevanovicInstitute for Medical Research, Military Medical Academy, Belgrade, Serbia.
Danilo VojvodicInstitute for Medical Research, Military Medical Academy, Belgrade, Serbia.
Aleksandra TopicDepartment for Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.ORCID 0000-0001-5618-752X
Aleksandra Petkovic-CurcinInstitute for Medical Research, Military Medical Academy, Belgrade, Serbia.
Kosovka Obradovic-DjuricicDepartment for Prosthetics, Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia.
Aleksa MarkovicDepartment for Oral Surgery, Faculty of Dental Medicine, University of Belgrade, Belgrade, Serbia.
Mirjana DjukicDepartment for Toxicology, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.ORCID 0000-0003-0177-1205
Dragana VujanovicDepartment for Toxicology, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Military Medical Academy · RSUniversity of Belgrade · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biocompatibility of dental materials (DM) can be evaluated by gingival crevicular fluid (GCF) oxidative stress (OS) status. The goal of the study was to ascertain influence of dental caries degree, teeth position, and type and amount of applied DM on GCF OS profile. For this purpose, we tested six DMs that were sealed in one session: amalgam (Amg), composites: Tetric EvoCeram and Beautifil (BF), phosphate cement-zinc phosphate and polycarboxylate cements-zinc polycarboxylate cements, and glass ionomer cement (GIC). The study included 88 dental outpatients. Follow-up was scheduled at 7th and 30th day. Oxidative stress parameters (malondialdehyde (MDA) and glutathione (GSH) levels and total superoxide dismutase (tSOD) activity) were measured before (0th day) and after the treatment (7th and 30th day) in GCF. Control teeth were mirror-positioned healthy teeth. The DM accomplished the following effects (listed in descending order): increase of GSH in GCF was realized by ZPoC > BF > GIC > Amg; tSOD activity increase by ZPoC > BF > Amg; and MDA decrease by ZPoC > ZPhC > Amg > TEC. Dental caries provokes insignificant rise of OS in GCF. ZPoC and ZPhC showed the highest antioxidant effect, contrary to GIC. Restorations with antioxidant properties may reduce gum diseases initiated by caries lesion, what is of great clinical relevance in dentistry.

Indexed as

AdolescentAdultAgedDental CariesGingival Crevicular FluidHumansMiddle AgedOxidative StressYoung Adult

Identifiers

PMID30140362
PMCPMC6081590
OpenAlexW2884503420

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.