Evidence map›Paper›PMID 30140124›Full record

ReviewJournal of orthopaedics2018

Are non-steroidal anti-inflammatory drug injections an alternative to steroid injections for musculoskeletal pain?: A systematic review.

Vandit Sardana, Joanna Burzynski, Khaled Hasan, Paul Zalzal

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Journal of orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06834425 (Efficacy of NSAID Peritendinous Injection for Acute Tendinitis), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06834425 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of NSAID Peritendinous Injection for Acute Tendinitis

TypeinterventionalSponsorTaipei Medical University WanFang HospitalRan2025 to 2026Enrolled40ConditionsTendinitis, Acute Tendonitis, NSAID (Non-Steroidal Anti-Inflammatory Drug)ArmsPeritendinous NSAID injection, Control group (placebo)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Vandit SardanaDivision of Orthopedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Joanna BurzynskiDepartment of Rehabilitation Sciences, McMaster University, Hamilton, Ontario, Canada.
Khaled HasanDivision of Orthopedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Paul ZalzalDivision of Orthopedic Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
McMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiven the potential side effect profile of steroids, the need for an alternative injectable anti-inflammatory is needed. The purpose of this systematic review was to compare corticosteroid injections with non-steroidal anti-inflammatory drug (NSAID) injections for musculoskeletal pain.

methodsReviewers with methodological and content expertise searched three databases: PUBMED, Medline and EMBASE. Two blinded reviewers searched, screened, and evaluated the data quality. Data was abstracted in duplicate. Agreement and descriptive statistics are presented.

resultsFour studies were included. All four studies found no statistically significant differences in improvements on the visual analog scale. The follow-up period within the four studies ranged between 2 weeks and 3 months. No statistically significant differences were demonstrated between the two groups with regards to functional outcomes.

interpretationThe studies reviewed, while limited in quantity, show that compared with corticosteroids, NSAIDs provide equivalent, if not better, pain relief from the musculoskeletal ailments assessed. Further, there is weak evidence supporting a lower recurrence rate of symptoms with NSAIDs when compared to corticosteroids. There is a need for more long-term high-quality studies on this topic. LEVEL OF EVIDENCE: Level II (Systematic review of Level II and III studies).

Indexed as

Intra-articular injectionsNSAIDSteroid

Identifiers

PMID30140124
PMCPMC6104144
OpenAlexW2885576350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.