Evidence map›Paper›PMID 30140055›Full record

ArticleScientific reports2018

Facile and inexpensive fabrication of zinc oxide based bio-surfaces for C-reactive protein detection.

Lu Cao, Janice Kiely, Martina Piano, Richard Luxton

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 32 citations in OpenAlex.

  1. Moderate molecular recognitions on ZnONanoscale advances · 2022
    Article
  2. Current Strategies and Potential Prospects for Nanoparticle-Mediated Treatment of Diabetic Nephropathy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Review
  3. Review
  4. Nano-engineered tools in the diagnosis, therapeutics, prevention, and mitigation of SARS-CoV-2.Journal of controlled release : official journal of the Controlled Release Society · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lu CaoInstitution of Bio-sensing Technology, University of the West of England, Frenchay Campus, Bristol, BS16 1QY, UK. Lu2.Cao@live.uwe.ac.uk.
Janice KielyInstitution of Bio-sensing Technology, University of the West of England, Frenchay Campus, Bristol, BS16 1QY, UK.
Martina PianoInstitution of Bio-sensing Technology, University of the West of England, Frenchay Campus, Bristol, BS16 1QY, UK.
Richard LuxtonInstitution of Bio-sensing Technology, University of the West of England, Frenchay Campus, Bristol, BS16 1QY, UK.
University of the West of England · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The paper reports a biosensor formed from antibody coated ZnO nano-crystals which has been prepared using a rapid and inexpensive fabrication method which utilises colloidal dispersion enhanced using sonication. This technique was used to prepare highly ordered and uniform nano-crystalline sensor surfaces on polyethylene terephthalate (PET) using 0.5%, 1% and 5% concentrations of zinc oxide nano-crystal suspensions. Impedance spectroscopy was employed to interrogate the sensor surfaces and confirmed high reproducibility of the fabrication process. Changes in impedance values, at a frequency of 138 Hz, were used to establish dose dependent responses for C-reactive protein (CRP) antigen. A limit of detection of less than 1 ng/ml was demonstrated for nano-surfaces fabricated from concentrations of 1% ZnO.

Indexed as

Biosensing TechniquesC-Reactive ProteinPolyethylene TerephthalatesZinc OxideC-Reactive ProteinPolyethylene TerephthalatesZinc Oxide

Identifiers

PMID30140055
PMCPMC6107546
OpenAlexW2885182645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.