ArticleHeredity2019
A Wolbachia infection from Drosophila that causes cytoplasmic incompatibility despite low prevalence and densities in males.
Article in Heredity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Continuously high Wolbachia incidence in flea populations may result from dual-strain infections with divergent effects.Scientific reports · 2025Article
- Wolbachia Feminises a Spider Host With Assistance From Co-Infecting Symbionts.Environmental microbiology · 2025Article
- Changes in the frequency of facultative endosymbionts in insect populations: overview and applications.Entomologia generalis · 2025Article
- Establishment of a Rapid Detection Method for Yeast-like Symbionts in Brown Planthopper Based on Droplet Digital PCR Technology.International journal of molecular sciences · 2023Article
- A male-killing Wolbachia endosymbiont is concealed by another endosymbiont and a nuclear suppressor.PLoS biology · 2023Article
- One strain may hide another: Cryptic male-killing Wolbachia.PLoS biology · 2023Article
- Wolbachia infection in native populations of Blattella germanica and Periplaneta americana.PloS one · 2023Article
- Does diet breadth affect the complexity of the phytophagous insect microbiota? The case study of Chrysomelidae.Environmental microbiology · 2022Article
- Article
- Sex-specific distribution and classification of Wolbachia infections and mitochondrial DNA haplogroups in Aedes albopictus from the Indo-Pacific.PLoS neglected tropical diseases · 2022Article
- High Incidence of RelatedInsects · 2021Article
- Prevalence and relationship of endosymbiotic Wolbachia in the butterfly genus Erebia.BMC ecology and evolution · 2021Article
- Article
- Environmental and Genetic Contributions to ImperfectGenetics · 2020Article
- Heatwaves cause fluctuations in wMel Wolbachia densities and frequencies in Aedes aegypti.PLoS neglected tropical diseases · 2020Article
- Evolutionary Ecology ofAnnual review of genetics · 2019Review
- Transfection of Culicoides sonorensis biting midge cell lines with Wolbachia pipientis.Parasites & vectors · 2019Article
- Quantitative methods for assessing local and bodywide contributions to Wolbachia titer in maternal germline cells of Drosophila.BMC microbiology · 2019Article
- Exposure to opposing temperature extremes causes comparable effects on Cardinium density but contrasting effects on Cardinium-induced cytoplasmic incompatibility.PLoS pathogens · 2019Article
- Effects of Alternative Blood Sources onInsects · 2018Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Wolbachia bacteria are common insect endosymbionts transmitted maternally and capable of spreading through insect populations by cytoplasmic incompatibility (CI) when infected males cause embryo death after mating with uninfected females. Selection in the Wolbachia endosymbiont occurs on female hosts and is expected to favour strong maternal transmission to female offspring, even at the cost of reduced CI. With maternal leakage, nuclear genes are expected to be selected to suppress cytoplasmic incompatibility caused by males while also reducing any deleterious effects associated with the infection. Here we describe a new type of Wolbachia strain from Drosophila pseudotakahashii likely to have arisen from evolutionary processes on host and/or Wolbachia genomes. This strain is often absent from adult male offspring, but always transmitted to females. It leads to males with low or non-detectable Wolbachia that nevertheless show CI. When detected in adult males, the infection has a low density relative to that in females, a phenomenon not previously seen in Wolbachia infections of Drosophila. This Wolbachia strain is common in natural populations, and shows reduced CI when older (infected) males are crossed. These patterns highlight that endosymbionts can have strong sex-specific effects and that high frequency Wolbachia strains persist through effects on female reproduction. Female-limited Wolbachia infections may be of applied interest if the low level of Wolbachia in males reduces deleterious fitness effects on the host.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.