Evidence map›Paper›PMID 30139920›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Long noncoding RNA

Abu Shufian Ishtiaq Ahmed, Kunzhe Dong, Jinhua Liu, Tong Wen, Luyi Yu, Fei Xu, Xiuhua Kang, Islam Osman, Guoqing Hu, Kristopher M Bunting and 10 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 1 synthesis or guideline pooled it, 135 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Unifying and unique roles of non-coding RNA biomarkers in liver and heart fibrosis.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026
    Review
  5. Review
  6. Review
  7. Long Non-Coding RNA Function in Smooth Muscle Cell Plasticity and Atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 3 countries.

Abu Shufian Ishtiaq AhmedDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA 30912.ORCID 0000-0002-7931-8972
Kunzhe DongDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA 30912.
Jinhua LiuDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanchang University, 330006 Nanchang, China.
Tong WenDepartment of Cardiology, The First Affiliated Hospital of Nanchang University, 330006 Nanchang, China.
Luyi YuDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanchang University, 330006 Nanchang, China.
Fei XuDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanchang University, 330006 Nanchang, China.
Xiuhua KangDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanchang University, 330006 Nanchang, China.
Islam OsmanDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA 30912.
Guoqing HuDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA 30912.
Kristopher M BuntingDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA 30912.
Danielle CrethersDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA 30912.
Hongyu GaoCenter for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN 46202.
Wei ZhangDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanchang University, 330006 Nanchang, China.
Yunlong LiuCenter for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN 46202.
Ke WenDepartment of Pharmacology, Tianjin Medical University, 300052 Tianjin, China.
Gautam AgarwalDepartment of Surgery, Medical College of Georgia, Augusta University, Augusta, GA 30912.
Tetsuro HiroseInstitute for Genetic Medicine, Hokkaido University, 060-0815 Sapporo, Japan.
Shinichi NakagawaRNA Biology Laboratory, Faculty of Pharmaceutical Sciences, Hokkaido University, 060-0815 Sapporo, Japan.
Almira VazdarjanovaDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA 30912.ORCID 0000-0002-3848-8895
Jiliang ZhouDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA 30912; JIZHOU@augusta.edu.ORCID 0000-0002-2375-4636
Augusta University · USNanchang University · CNHokkaido University · JPIndiana University School of MedicineTianjin Medical University · CN

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Role of Hippo-YAP Pathway in Smooth Muscle Phenotypic ModulationR01HL109605 · NHLBI · AUGUSTA UNIVERSITY · PI ZHOU, JILIANG · 2012 to 2016
$1.8M
Novel role of the lncRNA NEAT1 in smooth muscle phenotypic modulationR01HL132164 · NHLBI · AUGUSTA UNIVERSITY · PI ZHOU, JILIANG · 2016 to 2019
$1.5M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NHLBI NIH HHS R01 HL109605NHLBI NIH HHS R01 HL132164
6 · The paper itself

Abstract

In response to vascular injury, vascular smooth muscle cells (VSMCs) may switch from a contractile to a proliferative phenotype thereby contributing to neointima formation. Previous studies showed that the long noncoding RNA (lncRNA)

Indexed as

Gene Expression RegulationAnimalsCell MovementCell ProliferationCells, CulturedHumansMice, Inbred C57BLMice, KnockoutMuscle, Smooth, VascularMyocytes, Smooth MuscleNeointimaPhenotypeRatsRNA InterferenceRNA, Long NoncodingVascular System InjuriesNEAT1 long non-coding RNA, humanNEAT1 long non-coding RNA, mouseRNA, Long Noncodingepigenetic regulationgene expressionlong noncoding RNAphenotypic switchingsmooth muscle cells

Identifiers

PMID30139920
PMCPMC6140535
OpenAlexW2888247702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.