ArticleScience (New York, N.Y.)2018
Serotype-specific immunity explains the incidence of diseases caused by human enteroviruses.
Article in Science (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
74 citing papers in PubMed, 121 citations in OpenAlex.
- Hand, Foot, and Mouth Disease Surveillance in Anhui, After Introduction of the Enterovirus 71 Vaccine and During the COVID-19 Pandemic: Ecological Interrupted Time Series Study.JMIR public health and surveillance · 2026Article
- Genomic surveillance of enterovirus D68 circulating in 2025 reveals the emergence of a novel A2/B3 recombinant lineage.Microbiology spectrum · 2026Article
- Historical reconstruction of the earliest enterovirus A71 epidemics in Japan in the 1960s.Epidemiology and infection · 2026Article
- Spatiotemporal epidemiology and SARIMA-based forecasting of hand, foot, and mouth disease outbreak clusters in Beijing, 2019-2024.BMC infectious diseases · 2026Article
- Post-pandemic changes in population immunity have reduced the likelihood of emergence of zoonotic coronaviruses.Nature communications · 2026Article
- Global distribution and evolution of nine major non-polio enteroviruses revealed by genomic data mining.Biochemistry and biophysics reports · 2026Article
- Dynamics of endemic virus re-emergence in children in the USA following the COVID-19 pandemic (2022-23): a prospective, multicentre, longitudinal, immunoepidemiological surveillance study.The Lancet. Infectious diseases · 2026Article
- The Etiological Characteristics of Hand, Foot, and Mouth Disease in Yuyao, China, 2010-2023.Iranian journal of public health · 2025Article
- Epidemiological and Clinical Insights into Enterovirus Circulation in Europe, 2018-2023: A Multicenter Retrospective Surveillance Study.The Journal of infectious diseases · 2025Article
- Spatio-temporal dynamics of hand, foot and mouth disease in Malaysia, 2009-2019.PLoS neglected tropical diseases · 2025Article
- Enterovirus circulation in the WHO European region, 2015-2022: a comparison of data from WHO's three core poliovirus surveillance systems and the European Non-Polio Enterovirus Network (ENPEN).The Lancet regional health. Europe · 2025Article
- Return of the Biennial Circulation of Enterovirus D68 in Colorado Children in 2024 Following the Large 2022 Outbreak.Viruses · 2025Article
- Enterovirus A71 and coxsackievirus A6 circulation in England, UK, 2006-2017: A mathematical modelling study using cross-sectional seroprevalence data.PLoS pathogens · 2024Article
- A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models.Science translational medicine · 2024Article
- Inferring enterovirus D68 transmission dynamics from the genomic data of two 2022 North American outbreaks.Npj viruses · 2024Article
- Increasing intensity of enterovirus outbreaks projected with climate change.Nature communications · 2024Article
- Enteroviruses: epidemic potential, challenges and opportunities with vaccines.Journal of biomedical science · 2024Review
- Article
- Informing policy via dynamic models: Cholera in Haiti.PLoS computational biology · 2024Article
- Seasonal Testing, Results, and Effect of the Pandemic on Coxsackievirus Serum Studies.Microorganisms · 2024Article
14 more citing papers are in PubMed but not listed here.
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2 authors at 1 institution in 1 country.
Funding
Abstract
Human enteroviruses are a major cause of neurological and other diseases. More than 100 serotypes are known that exhibit unexplained complex patterns of incidence, from regular cycles to more irregular patterns, and new emergences. Using 15 years of surveillance data from Japan (2000-2014) and a stochastic transmission model with accurate demography, we show that acquired serotype-specific immunity can explain the diverse patterns of 18 of the 20 most common serotypes (including Coxsackieviruses, Echoviruses, and Enterovirus-A71). The remaining two serotypes required a change in viral characteristics, including an increase in pathogenicity for Coxsackievirus-A6, which is consistent with its recent global rise in incidence. On the basis of our findings, we are able to predict outbreaks 2 years ahead of time (2015-2016). These results have implications for the impact of vaccines under development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.