ArticleThe oncologist2019
Patient-Clinician Discordance in Perceptions of Treatment Risks and Benefits in Older Patients with Acute Myeloid Leukemia.
Article in The oncologist, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05061095 (Understanding What Matters Most to Patients), which is not on this map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Understanding What Matters Most to Patients: Establishing the Validity of a Best-Worst Scaling Survey
Who cites it
42 citing papers in PubMed.
- Concordance Between Patient-Reported and Clinically Documented Symptoms in Acute Myeloid Leukemia.Oncology nursing forum · 2026Article
- Awareness of disease extent and perceived palliative treatment goals among oncology patients: a multicenter study.Scientific reports · 2026Article
- Perceptions of the Values and Outcomes to Improve Cancer Experiences (VOICE) tool: a digital values-clarification instrument and tailored summary report for older adults with advanced cancer.Journal of patient-reported outcomes · 2026Article
- Advancing Knowledge of Values-Clarification Processes During Complex Decision-Making Among Older Adults With Advanced Cancer: Protocol for a Pilot Randomized Trial Using Simulated Patient-Clinician Encounters.JMIR research protocols · 2025Article
- Protocol of a decisional intervention for older adults with newly diagnosed acute myeloid leukemia and their caregivers: UR-GOAL 3.Journal of geriatric oncology · 2025Article
- Development and alpha-testing of a patient decision aid for patients with chronic myeloid leukemia regarding dose reduction.BMC medical informatics and decision making · 2024Article
- Quality of end-of-life care in patients with hematological malignancies: potential role of palliative care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Observational
- Balancing risks and rewards: How hematologists discuss uncertainty in allogeneic hematopoietic cell transplantation outcomes.Patient education and counseling · 2024Article
- UK national observational cohort study investigating Tolerance of Anti-cancer Systemic Therapy in the Elderly: the TOASTIE study.BMJ oncology · 2024Article
- Participation and Influencing Factors in the Decision-Making of Life-Sustaining Treatment: A Focus on Deceased Patients with Hematologic Neoplasms.Journal of hospice and palliative care · 2023Article
- Advancing Palliative Care Integration in Hematology: Building Upon Existing Evidence.Current treatment options in oncology · 2023Review
- Palliative Care in Patients with Hematological Malignancies.Florence Nightingale journal of nursing · 2023Article
- Older patients' experiences following initial diagnosis of acute myeloid leukemia: A qualitative study.Journal of geriatric oncology · 2022Article
- Code status transitions in patients with high-risk acute myeloid leukemia.Blood advances · 2022Article
- Development of a Patient-Centered Preference Tool for Patients With Hematologic Malignancies: Protocol for a Mixed Methods Study.JMIR research protocols · 2022Article
- "You have to be sure that the patient has the full picture": Adaptation of the Best Case/Worst Case communication tool for geriatric oncology.Journal of geriatric oncology · 2022Article
- Characterizing uncertainty in goals-of-care discussions among black and white patients: a qualitative study.BMC palliative care · 2022Article
- Association of Prognostic Understanding With Health Care Use Among Older Adults With Advanced Cancer: A Secondary Analysis of a Cluster Randomized Clinical Trial.JAMA network open · 2022Article
- Early Palliative Care in Acute Myeloid Leukemia.Cancers · 2022Review
- The relationship between emotional well-being and understanding of prognosis in patients with acute myeloid leukemia (AML).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Observational
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
backgroundOlder patients (≥60 years) with acute myeloid leukemia (AML) face difficult decisions regarding treatment with "intensive" chemotherapy that carries significant toxicity for a small chance of a cure versus "nonintensive" chemotherapy to control the disease, but with fewer side effects. However, studies of how these patients understand the risks and benefits of such treatments are lacking.
methodsWe conducted a longitudinal study of older patients newly diagnosed with AML assessing patients' (
resultsWe enrolled patients within 72 hours of initiating intensive (
conclusionOlder patients with AML overestimate the risks and benefits of treatment. Interventions to facilitate communication and enhance patients' understanding of the goals of therapy and treatment risk are needed. IMPLICATIONS FOR PRACTICE: Older patients with acute myeloid leukemia (AML) are confronted with challenging decisions regarding treatment with "intensive" chemotherapy that carries significant toxicity for a small chance of a cure versus "nonintensive" chemotherapy to control the disease, but with fewer side effects. A clear understanding of the likely outcome and risks of the various treatment strategies is essential for these patients to make informed decisions about their care. This article reports that older patients with AML overestimate both the risks and benefits of treatment and have substantial misperceptions about their prognosis. Interventions to enhance patients' understanding of their prognosis and treatment risk are needed.
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