Evidence map›Paper›PMID 30139766›Full record

ArticleHospital pediatrics2018

Variation in Diagnostic Test Use and Associated Outcomes in Staphylococcal Scalded Skin Syndrome at Children's Hospitals.

Hannah C Neubauer, Matt Hall, Sowdhamini S Wallace, Andrea T Cruz, Mary Ann Queen, Dana M Foradori, Paul L Aronson, Jessica L Markham, Jennifer A Nead, Gabrielle Z Hester and 2 more

Abstract read
In one paragraph

Article in Hospital pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Hannah C NeubauerSection of Pediatric Hospital Medicine, Department of Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas; hcneubau@texaschildrens.org.
Matt HallDepartment of Biostatistics, Children's Hospital Association, Lenexa, Kansas.
Sowdhamini S WallaceSection of Pediatric Hospital Medicine, Department of Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas.
Andrea T CruzSections of Pediatric Emergency Medicine and Pediatric Infectious Diseases, Baylor College of Medicine, Houston, Texas.
Mary Ann QueenDivisions of Pediatric Hospital Medicine and Infectious Diseases, Children's Mercy Kansas City, Kansas City, Missouri.
Dana M ForadoriSection of Pediatric Hospital Medicine, Department of Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas.
Paul L AronsonSection of Pediatric Emergency Medicine, Departments of Pediatrics and Emergency Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut.
Jessica L MarkhamDivisions of Pediatric Hospital Medicine and Infectious Diseases, Children's Mercy Kansas City, Kansas City, Missouri.
Jennifer A NeadDepartment of Pediatrics, Upstate Golisano Children's Hospital, Syracuse, New York; and.
Gabrielle Z HesterDepartment of Hospital Medicine, Children's Minnesota, Minneapolis, Minnesota.
Russell J McCullohDivisions of Pediatric Hospital Medicine and Infectious Diseases, Children's Mercy Kansas City, Kansas City, Missouri.
Michelle A LopezSection of Pediatric Hospital Medicine, Department of Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas.
Baylor College of Medicine · USChildren's Mercy Hospital · USChildren's Hospital Association · USChildren's Minnesota · USGolisano Children's Hospital · USTexas Children's Hospital · USYale University · US

Funding

Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
NCATS NIH HHS KL2 TR001862
6 · The paper itself

Abstract

objectivesThe incidence of staphylococcal scalded skin syndrome (SSSS) is rising, but current practice variation in diagnostic test use is not well described. Our aim was to describe the variation in diagnostic test use in children hospitalized with SSSS and to determine associations with patient outcomes.

methodsWe performed a retrospective (2011-2016) cohort study of children aged 0 to 18 years from 35 children's hospitals in the Pediatric Health Information System database. Tests included blood culture, complete blood count, erythrocyte sedimentation rate, C-reactive protein level, serum chemistries, and group A streptococcal testing. K-means clustering was used to stratify hospitals into groups of high (cluster 1) and low (cluster 2) test use. Associations between clusters and patient outcomes (length of stay, cost, readmissions, and emergency department revisits) were assessed with generalized linear mixed-effects modeling.

resultsWe included 1259 hospitalized children with SSSS; 84% were ≤4 years old. Substantial interhospital variation was seen in diagnostic testing. Blood culture was the most commonly obtained test (range 62%-100%), with the most variation seen in inflammatory markers (14%-100%). Between hospital clusters 1 and 2, respectively, there was no significant difference in adjusted length of stay (2.6 vs 2.5 days;

conclusionsFor children hospitalized with SSSS, lower use of diagnostic tests was not associated with changes in outcomes. Hospitals with high diagnostic test use may be able to reduce testing without adversely affecting patient outcomes.

Indexed as

Hospitals, PediatricAdolescentBlood Cell CountBlood Chemical AnalysisBlood CultureBlood SedimentationChildChild, PreschoolCohort StudiesC-Reactive ProteinEmergency Service, HospitalFemaleHealth Care CostsHematologic TestsHumansInfantC-Reactive Protein

Identifiers

PMID30139766
PMCPMC6317540
OpenAlexW2889416111

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.