Evidence map›Paper›PMID 30139739›Full record

ArticleThe Journal of cell biology2018

Spatial control of Draper receptor signaling initiates apoptotic cell engulfment.

Adam P Williamson, Ronald D Vale

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Dynamics of phagocytosis mediated by phosphatidylserine.Biochemical Society transactions · 2022
    Review
  13. Article
  14. Article
  15. Phase separation in immune signalling.Nature reviews. Immunology · 2022
    Review
  16. Article
  17. Article
  18. Review
  19. Phagocyte Responses to Cell Death in Flies.Cold Spring Harbor perspectives in biology · 2020
    Review
  20. Die in pieces: How Drosophila sheds light on neurite degeneration and clearance.Journal of genetics and genomics = Yi chuan xue bao · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Adam P WilliamsonDepartment of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA.ORCID 0000-0001-8905-5646
Ronald D ValeDepartment of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA ron.vale@ucsf.edu.ORCID 0000-0003-3460-2758
Howard Hughes Medical Institute · US

Funding

Regulation of Microtubule-Based MotilityR35GM118106 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VALE, RONALD D · 2016 to 2020
$1.7M
LTQ XL Linear Quadrupole Ion Trap Mass SpectrometerS10RR025622 · NCRR · UNIVERSITY OF CALIFORNIA BERKELEY · PI KOHLSTAEDT, LORI · 2009 to 2009
$463k
NCRR NIH HHS S10 RR025622NIGMS NIH HHS R35 GM118106
6 · The paper itself

Abstract

The engulfment of apoptotic cells is essential for tissue homeostasis and recovering from damage. Engulfment is mediated by receptors that recognize ligands exposed on apoptotic cells such as phosphatidylserine (PS). In this study, we convert

Indexed as

ApoptosisSignal TransductionAnimalsCell LineDrosophila melanogasterDrosophila ProteinsMembrane ProteinsDrosophila Proteinsdrpr protein, DrosophilaMembrane Proteins

Identifiers

PMID30139739
PMCPMC6219719
OpenAlexW2888357434

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.