Evidence map›Paper›PMID 30139738›Full record

ArticleMolecular cancer research : MCR2018

"Z4" Complex Member Fusions in NUT Carcinoma: Implications for a Novel Oncogenic Mechanism.

Hitoshi Shiota, Janine E Elya, Artyom A Alekseyenko, Pauline M Chou, Shelby A Gorman, Olena Barbash, Kelly Becht, Kristina Danga, Mitzi I Kuroda, Valentina Nardi and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular cancer research : MCR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. [NUT cancer of nasal cavity and sinuses: a case report and literature review].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Zinc Finger MYND-Type Containing 8 (ZMYND8) Is Epigenetically Regulated in Mutant Isocitrate Dehydrogenase 1 (IDH1) Glioma to Promote Radioresistance.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  16. Review
  17. Article
  18. Review
  19. Report of the First International Symposium on NUT Carcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Hitoshi ShiotaDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-9548-1411
Janine E ElyaDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Artyom A AlekseyenkoDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Pauline M ChouDepartment of Pathology and Laboratory Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
Shelby A GormanCancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania.
Olena BarbashCancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania.
Kelly BechtDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Kristina DangaDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Mitzi I KurodaDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Valentina NardiDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Christopher A FrenchDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. cfrench@bwh.harvard.edu.ORCID 0000-0002-7434-4987
Brigham and Women's Hospital · USGlaxoSmithKline (United States) · USLurie Children's Hospital · USMassachusetts General Hospital · US

Funding

Pathogenesis of NUT-Rearranged CarcinomaR01CA124633 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI Christopher A French · 2007 to 2026
$7.0M
Comprehensive analysis of epigenetic regulators in their native chromatin contextR01GM101958 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI KURODA, MITZI I · 2012 to 2018
$2.4M
NCI NIH HHS R01 CA124633NIGMS NIH HHS R01 GM101958
6 · The paper itself

Abstract

Nuclear protein in testis (NUT) carcinoma (NC) is a rare, distinctly aggressive subtype of squamous carcinoma defined by the presence of

Indexed as

AdolescentCarcinoma, Squamous CellCell Line, TumorCell NucleusCell SurvivalDNA-Binding ProteinsFemaleHigh-Throughput Nucleotide SequencingHumansIn Situ Hybridization, FluorescenceNeoplasm ProteinsNuclear ProteinsOncogene Proteins, FusionSequence Analysis, DNATumor Suppressor ProteinsBRD4-NUT fusion oncogene protein, humanDNA-Binding ProteinsNeoplasm ProteinsNuclear ProteinsNUTM1 protein, humanOncogene Proteins, FusionTumor Suppressor ProteinsZMYND8 protein, humanZNF592 protein, human

Identifiers

PMID30139738
PMCPMC6279489
OpenAlexW2888684537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.